23185-09-3

Basic information

• Product Name: 2-propyl-4,5-dihydro-1,3-thiazole
• Synonyms: Thiazole, 4,5-dihydro-2-propyl
• CAS NO: 23185-09-3
• Molecular Formula: C₆H₁₁NS
• Molecular Weight: 129.2232
• Mol File: 23185-09-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 179.5°C at 760 mmHg
• Flash Point: 62.4°C
• Density: 1.08g/cm³
• Vapor Pressure: 1.27mmHg at 25°C
• Refractive Index: 1.559
• CAS DataBase Reference: 2-propyl-4,5-dihydro-1,3-thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-propyl-4,5-dihydro-1,3-thiazole(23185-09-3)
• EPA Substance Registry System: 2-propyl-4,5-dihydro-1,3-thiazole(23185-09-3)

Safety Data

• Hazardous Substances Data: 23185-09-3(Hazardous Substances Data)

Upstream product

• 109-74-0 propyl cyanide 
• 156-57-0 2-mercaptoethylamine hydrochloride 
• 5842-00-2 2-(butylamino)ethanethiol 
• 24050-10-0 2-propyl-thiazolidine 
• 123-72-8 butyraldehyde 
• 60-23-1 Cysteamine 
• 23363-91-9 N-(2-hydroxyethyl)butyramide 
• 74-85-1 ethene 

Downstream Products

• 40052-05-9 N-benzoyl-thioglycine S-{2-[1-(5-oxo-2-phenyl-oxazol-4-ylidene)-butylamino]-ethyl} ester 

Relevant articles and documents

Novel synthesis of 2-thiazolines

The synthesis of a series of 2-thiazolines was carried out under mild conditions from the corresponding thiazolidines, by a Ru-catalyzed/TBHP oxidation reaction conditions. The reaction was chemoselective towards the amine-imine oxidation and was also regioselective, affording the unsaturation at the 2-position of the heterocycle, even with thiazolidine substrates bearing ester groups at the 4-position. (C) 2000 Elsevier Science Ltd.

Easy access to 2-alkyl and 2-arylthiazolines using a modified heteropolyacid catalysis: Application to the synthesis of bacillamide A

A straightforward access to 2-alkyl and 2-arylthiazolines by condensation of-aminothiols on nitriles, catalyzed by phosphotungstic acid (2%) under microwave irradiation, is described. This method has been directly applied to a short and efficient synthesi

Routes of photocatalytic destruction of chemical warfare agent simulants

Selected imitants of chemical warfare agents such as dimethyl methylphosphonate (DMMP), diethyl phosphoramidate (DEPA), pinacolyl methylphosphonate (PMP), butylaminoethanethiol (BAET) were subjected to photocatalytic and sonophotocatalytic treatment in aqueous suspensions of TiO2. Complete conversion of the same mass of imitants to inorganic products was obtained within 600 min for DMMP, DEPA, PMP, but required a longer time for BAET. Sonolysis accelerated photodegradation of DMMP. No degradation was observed without ultraviolet illumination. Final products of degradation were PO43-, CO2 for DMMP and PMP, PO43-, NO3- (25%), NH4+ (75%), CO2 for DEPA, and SO42-, NH4+, CO2 for BAET. The number of main detected intermediate products increases in the order DMMP (7), DEPA (9), PMP (21), and exceeds 34 for BAET. Degradation of DMMP mainly proceeds through consecutive oxidation of methoxy groups and then the methyl group. Dimethyl hydroxymethylphosphonate and dimethylphosphate testify to the parallel oxidation of the methyl group. Destruction of DEPA mainly starts with cleavage of the P-NH2 bond to form diethyl phosphate, which transforms further into ethyl phosphate. Oxidation of α and β carbons of ethoxy groups to form ethylphosphonoamidate, hydroxyethyl ethylphosphonoamidate and other products also contributes to the destruction. Photocatalytic degradation of PMP mainly starts with oxidation of the pinacolyl fragment, methylphosphonic acid and acetone being the major products. Oxidation of BAET begins with dark dimerization to disulfide, which undergoes oxidation of sulfur forming sulfinic and sulfonic acids as well as oxidation of carbons to form butanal, aminobutane, etc., and cyclic products such as 2-propylthiazole. A scheme of degradation was proposed for DMMP and DEPA, and starting routes for PMP and BAET. Quantum efficiencies of complete mineralization calculated as reaction rate to photon flux ratio approximate 10-3%.