23624-64-8

Basic information

• Product Name: 4-(benzoylamino)-1-(2,3,5-tri-O-benzoylpentofuranosyl)pyrimidin-2(1H)-one
• CAS NO: 23624-64-8
• Molecular Formula: C₃₇H₂₉N₃O₉
• Molecular Weight: 659.6409
• Mol File: 23624-64-8.mol
• Article Data: 14

Chemical Properties

• Density: 1.35g/cm³
• Refractive Index: 1.648
• CAS DataBase Reference: 4-(benzoylamino)-1-(2,3,5-tri-O-benzoylpentofuranosyl)pyrimidin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(benzoylamino)-1-(2,3,5-tri-O-benzoylpentofuranosyl)pyrimidin-2(1H)-one(23624-64-8)
• EPA Substance Registry System: 4-(benzoylamino)-1-(2,3,5-tri-O-benzoylpentofuranosyl)pyrimidin-2(1H)-one(23624-64-8)

Safety Data

• Hazardous Substances Data: 23624-64-8(Hazardous Substances Data)

Upstream product

• 613-90-1 benzoyl cyanide 
• 65-46-3 CYTIDINE 
• 918800-27-8 p-tolyl 2,3,5-tri-O-benzoyl-1-thio-β-D-ribofuranoside 
• 64339-87-3 N₄,O-bis(trimethylsilyl)-N₄-benzoylcytosine 
• 26661-13-2 4-N-benzoylcytosine 
• 115459-50-2 2,3,5-Tri-O-benzoyl-D-ribofuranose 
• 6974-32-9 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose 
• 151867-55-9 2,3,5-tri-O-benzoyl-β-D-ribofuranosyl methyl carbonate 
• 85743-99-3 N-(2-Trimethylsilanyloxy-pyrimidin-4-yl)-benzamide 
• 98-88-4 benzoyl chloride 

Downstream Products

• 6554-15-0 N⁴-benzoyl-5'-O-benzoylcytidine 
• 6554-17-2 N⁴-benzoyl-3',5'-di-O-benzoylcytidine 
• 6554-16-1 N⁴,O^2'_,O5'-tribenzoyl-cytidine 
• 74829-53-1 5,6-dihydro-N⁴-hydroxy-6-hydroxyamino-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)cytosine 
• 31652-74-1 2',3',5'-tri-O-benzoyl-L-cytidine 
• 65-46-3 CYTIDINE 
• 1748-04-5 tribenzoyl uridine 

Relevant articles and documents

Ortho-(1-phenylvinyl)benzoate glycosylation donor, and preparation method and application thereof

The invention discloses an ortho-(1-phenylvinyl)benzoate glycosylation donor, and a preparation method and an application thereof in a glycosylation reaction. The ortho-(1-phenylvinyl)benzoate glycosylation donor is stable, is easy to prepare and store, and is widely applied to the construction of various oxygen glucosides and nucleoside (nitrogen glucoside) glycosidic bonds. The leaving group ofthe donor is an alkenyl ester, has a high activity, and can be combined with thioglycoside or n-pentenyl ether glucoside through a one-pot glycosylation reaction to synthesize oligosaccharide. The glycosylation reaction conditions are mild, and receptors sensitive to acid and electrophilic reagents can tolerate the glycosylation reaction conditions.

Propargyl 1,2-orthoesters for a catalytic and stereoselective synthesis of pyrimidine nucleosides

Pyrimidine nucleosides are synthesized by using propargyl 1,2-orthoesters and Au(III) salt as a catalyst. Strategically positioned 1,2-orthoesters are found to yield only 1,2-trans nucleosides and enable preparation of 2′-OH containing pyrimidine nucleosides. The glycosyl donor employed in this study is stable and easily accessible. The identified high-yielding protocol is mild, diastereoselective, and catalytic.

An efficient approach to the synthesis of nucleosides: Gold(I)-catalyzed N-glycosylation of pyrimidines and purines with glycosyl ortho-alkynyl benzoates

Persuaded with gold: The title reaction in the presence of [Ph 3PAuNTf2] (Tf=trifluoromethanesulfonyl) led conveniently to the corresponding nucleosides with excellent regioselectivity (see scheme). Even purine derivatives underwent this transformation owing to the mild conditions, which enabled the use of protecting groups that would not usually be compatible with N-glycosylation conditions. Copyright