2373-76-4 Usage
Description
2-Methylcinnamic acid, also known as 3-phenylpropenoic acid, is an organic compound that belongs to the family of cinnamic acids. It is characterized by its white flake or crystal appearance and has been reported to exhibit strong anti-fungal activity against various types of fungi, such as white-rot fungus Lenzites betulina and brown-rot fungus Laetiporus sulphureus. The hydrogenation of 2-methylcinnamic acid using Walphos ligands and their biferrocene analogs has also been studied.
Uses
Used in Pharmaceutical Industry:
2-Methylcinnamic acid is used as a starting reagent for the total synthesis of the cytotoxic alkaloid, 22-hydroxyacuminatine. This alkaloid has potential applications in the development of new drugs for the treatment of various diseases, including cancer.
Used in Chemical Synthesis:
2-Methylcinnamic acid is used in the preparation of (E)-2-methylcinnamic acid i-butylammonium salt, which is an important intermediate in the synthesis of various chemical compounds. This salt can be utilized in the production of different chemicals and materials, contributing to the advancement of the chemical industry.
Used in Antifungal Applications:
Due to its strong anti-fungal activity, 2-Methylcinnamic acid can be employed as an active ingredient in the development of antifungal agents. These agents can be used in the agricultural industry to protect crops from fungal infections, as well as in the medical field for the treatment of fungal infections in humans and animals.
Used in Research and Development:
The study of hydrogenation of 2-methylcinnamic acid using Walphos ligands and their biferrocene analogs can lead to the discovery of new catalysts and reaction mechanisms. This research can have implications in various fields, including materials science, pharmaceuticals, and environmental science, where efficient and selective catalysts are in high demand.
Check Digit Verification of cas no
The CAS Registry Mumber 2373-76-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,7 and 3 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2373-76:
(6*2)+(5*3)+(4*7)+(3*3)+(2*7)+(1*6)=84
84 % 10 = 4
So 2373-76-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H10O2/c1-8-4-2-3-5-9(8)6-7-10(11)12/h2-7H,1H3,(H,11,12)/b7-6+
2373-76-4Relevant articles and documents
H NMR evidence for the formation of vinyllead triacetates. The reactions of vinylmercury, vinyltin, and vinylboronic acids with lead tetraacetate
Parkinson, Christopher J.,Stoermer, Martin J.
, p. 207 - 214 (1996)
Vinylmercury compounds, vinylboronic acids and vinylstannanes undergo rapid metal-lead exchange with lead tetraacetate in deuterochloroform to generate vinyllead triacetates, which have been characterised by their 1H-1H and 207Pb-1H coupling constants. In addition, a number of divinyl and mixed aryl-vinyllead dicarboxylates have been prepared via boron-lead exchange.
Iron-catalyzed domino decarboxylation-oxidation of α,β-unsaturated carboxylic acids enabled aldehyde C-H methylation
Gong, Pei-Xue,Xu, Fangning,Cheng, Lu,Gong, Xu,Zhang, Jie,Gu, Wei-Jin,Han, Wei
supporting information, p. 5905 - 5908 (2021/06/18)
A practical and general iron-catalyzed domino decarboxylation-oxidation of α,β-unsaturated carboxylic acids enabling aldehyde C-H methylation for the synthesis of methyl ketones has been developed. This mild, operationally simple method uses ambient air as the sole oxidant and tolerates sensitive functional groups for the late-stage functionalization of complex natural-product-derived and polyfunctionalized molecules.
Method for preparing alpha, beta-unsaturated carboxylic acid compound
-
Paragraph 0103-0104; 0431-0438, (2021/05/05)
The invention discloses a method for preparing an alpha, beta-unsaturated carboxylic acid compound, which comprises the following steps: 1) in an atmosphere containing carbon dioxide, heating and reacting a mixture containing hydrosilane and a copper catalyst to obtain a system I; and 2) adding a raw material containing alkyne and a nickel catalyst into the system I in the step 1), and heating to react. The method has the advantages of simple, easily available, cheap and stable raw materials, common, easily available and stable catalyst, mild reaction conditions, simple post-treatment, high yield and the like.
