23761-23-1 Usage
Description
3-Oxocyclobutanecarboxylic acid, with the CAS number 23761-23-1, is a white solid compound that is utilized in various organic synthesis processes. It serves as a key intermediate in the creation of different chemical compounds and materials.
Uses
Used in Organic Synthesis:
3-Oxocyclobutanecarboxylic acid is used as a synthetic building block for the production of various organic compounds. Its unique structure and reactivity make it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Oxocyclobutanecarboxylic acid is used as a key intermediate in the development of new drugs. Its incorporation into drug molecules can enhance their efficacy, selectivity, and pharmacokinetic properties, leading to improved therapeutic outcomes.
Used in Agrochemical Industry:
3-Oxocyclobutanecarboxylic acid is also employed in the agrochemical industry for the synthesis of novel pesticides and other crop protection agents. Its use in this sector can contribute to the development of more effective and environmentally friendly products.
Used in Specialty Chemicals:
3-Oxocyclobutanecarboxylic acid finds application in the production of specialty chemicals, such as additives, coatings, and polymers. Its versatility in organic synthesis allows for the creation of innovative materials with unique properties and applications.
Synthesis Reference(s)
The Journal of Organic Chemistry, 53, p. 3841, 1988 DOI: 10.1021/jo00251a033
Check Digit Verification of cas no
The CAS Registry Mumber 23761-23-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,7,6 and 1 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 23761-23:
(7*2)+(6*3)+(5*7)+(4*6)+(3*1)+(2*2)+(1*3)=101
101 % 10 = 1
So 23761-23-1 is a valid CAS Registry Number.
InChI:InChI=1/C5H6O3/c6-4-1-3(2-4)5(7)8/h3H,1-2H2,(H,7,8)
23761-23-1Relevant articles and documents
Preparation method 3 - oxocyclobutane-based carboxylic acid
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Paragraph 0033-0035, (2021/10/27)
The invention discloses a preparation method of 3 -oxocyclobutane-based carboxylic acid, and belongs to the technical field of synthesis of medical intermediates. The ketone is protected from 1, 3 -dihydroxyacetone by condensation with trimethyl orthoformate to give 2, 2 -dimethoxy -1, 3 -propanediol, followed by reaction with malonate to give 3, 3 -dimethylcyclobutyl -1, 1 -dicarboxylic acid diester, followed by hydrolysis under acidic conditions. Decarboxylation and deprotection to yield 3 -oxocyclobutane-based carboxylic acids. The method has the advantages of high yield, common and easily available raw materials, simple flow and industrial amplification prospect.
Preparation method of 3-oxocyclobutylcarboxylic acid
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Paragraph 0028-0084, (2019/01/24)
The invention belongs to the technical field of organic synthesis, and specifically relates to a preparation method of 3-oxocyclobutylcarboxylic acid. According to the preparation method, 3,3-dimethoxylcyclobutyl-1,1-diisopropyl dicarboxylate, methanol, and sodium hydroxide are taken as the raw materials, and raw materials react with hydrochloric acid to prepare 3-oxocyclobutylcarboxylic acid. Thereactions are quick, the method is simple, the technology is safe, the raw materials are easily available and cheap, the yield of the two-step reactions can reach 80% or more, and the production purity and yield are effectively increased.
ANTIBACTERIAL AGENTS
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Page/Page column 105, (2014/10/18)
Antibacterial compounds of formula (I) are provided, as well as stereoisomers and pharmaceutically acceptable salts and esters thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.
