2412-72-8Relevant articles and documents
19-nor steroids having a thiocarbonated chain in position 11beta, their preparation process and the intermediates of this process, and the intermediates of this process, their use as medicaments and compositions
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, (2008/06/13)
Compounds of formula (I), wherein R17and R′17are such that: either R17and R′17together form ketone, hydrazono, oxime or methylene, or R17is hydroxyl, hydroxymethyl or acyloxy and R′17is hydrogen, alkyl or optionally substitued alkenyl or alkynyl; R3is hydrogen or alkyl; R16is hydrogen, halogen or alkyl; m is 0, 1 or 2; X, Y and Z are such that: X is methylene, arylene or arylenoxy bonded to the steroid by a carbon atom; Y is a saturated or unsaturated straight or branched aliphatic chain which is optionally interrupted by oxygen; and Z is aryl, arylalkyl or straight or branched alkyl; addition salts thereof, a preparation method therefor, medicinal uses thereof, compositions containing said compounds, and resulting novel intermediates.