24242-77-1

Basic information

• Product Name: Ethanone, 2-iodo-1,2-diphenyl-
• CAS NO: 24242-77-1
• Molecular Formula: C14H11IO
• Molecular Weight: 322.145
• Mol File: 24242-77-1.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-iodo-1,2-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-iodo-1,2-diphenyl-(24242-77-1)
• EPA Substance Registry System: Ethanone, 2-iodo-1,2-diphenyl-(24242-77-1)

Safety Data

• Hazardous Substances Data: 24242-77-1(Hazardous Substances Data)

Upstream product

• 447-31-4 Desyl chloride 
• 26226-48-2 1,2-diphenyl-1-nitrooxirane 
• 501-65-5 diphenyl acetylene 
• 451-40-1 phenyl benzyl ketone 
• 1484-50-0 desyl bromide 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 67-56-1 methanol 
• 119-53-9 2-hydroxy-2-phenylacetophenone 

Downstream Products

• 108478-16-6 3-Hydroxy-1,2-diphenyl-1-propanone 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 475086-75-0 4-[N-(5,6-diphenylpyrazine-2-yl)-N-isopropylamino]-1-butanol 
• 29864-19-5 2-(2-nitrophenyl)-4,5-diphenylimidazole 
• 1728-95-6 2-(4-methoxy-phenyl)-4,5-diphenyl-1H-imidazole 
• 2284-96-0 2-(4-fluorophenyl)-4,5-diphenyl-1H-imidazole 
• 14359-34-3 3-(4,5-diphenyl-1H-imidazol-2-yl)-1H-indole 
• 29916-33-4 2-(furan-2-yl)-4,5-diphenyl-1H-imidazole 
• 13866-85-8 2‐(naphthalen‐2‐yl)‐4,5‐diphenyl‐1H‐imidazole 
• 1740-26-7 2-(2-fluorophenyl)-4,5-diphenyl-1H-imidazole 
• 1965-19-1 2-(2-methoxyphenyl)-4,5-diphenyl-1H-imidazole 
• 5496-38-8 2-(3-nitrophenyl)-4,5-diphenyl-1H-imidazole 
• 134-81-6 benzil 
• 5496-31-1 2-(4-methylphenyl)-4,5-diphenyl-1H-imidazole 

Relevant articles and documents

Molecular iodine/DMSO mediated oxidation of internal alkynes and primary alcohols using a one-pot, two step approach towards 2,4,5-trisubstituted imidazoles: Substrate scope and mechanistic studies

An efficient, eco-friendly and practical oxidation of internal alkynes and primary alcohols as key steps towards the synthesis of 2,4,5-trisubstituted imidazoles is reported. This green synthetic methodology employed an acid and metal-free molecular iodine/DMSO system, to afford a variety of substituted imidazoles in moderate to good yields, with a range of functionalities tolerated. Mechanistic studies revealed two distinct oxidation pathways, which ultimately form the diketone and aldehyde that serve as key intermediates in the multicomponent domino synthesis.

High yield preparation method of selexipag intermediate compound under middle conditions

The invention relates to a high yield preparation method of a selexipag intermediate compound under middle conditions. According to the method, styracitol and halogen acid carry out halogenation reactions, and the reaction product and N-aminoacetyl-N-isopropyl n-butanol carry out condensation, ammoxidation, and ring forming reactions to obtain 2-(N-isopropyl-N-4-hydroxylbutyl)amino-5,6-diphenylpyrazine. The compound can be used to prepare selexipag. The raw materials are cheap and easily available, the operation is simple, convenient and safe, the reaction selectivity is good, the yield and purity are high, and the cost is low.

Iodination of alcohols over Keggin-type heteropoly compounds: A simple, selective and expedient method for the synthesis of alkyl iodides

Different catalysts derived from Keggin-type heteropoly compounds were prepared and their catalytic activities have been compared in the iodination of benzyl alcohol with KI under mild reaction conditions. A high catalytic activity was found over tungstophosphoric acid supported on silica and titania. The effect of catalyst loading, iodine source and the nature of substituents on the aromatic ring of benzyl alcohol were investigated. Finally, several competitive reactions were studied between structurally diverse alcohols. This protocol provides a mild and expedient way for the conversion of various alcohols to their corresponding alkyl iodides with high selectivity.