24265-37-0

Basic information

• Product Name: 2,2,2-trifluoroethoxide
• Synonyms: 2,2,2-trifluoroethoxide
• CAS NO: 24265-37-0
• Molecular Weight: 99.0325
• Mol File: 24265-37-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2,2,2-trifluoroethoxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-trifluoroethoxide(24265-37-0)
• EPA Substance Registry System: 2,2,2-trifluoroethoxide(24265-37-0)

Safety Data

• Hazardous Substances Data: 24265-37-0(Hazardous Substances Data)

Upstream product

• 77568-66-2 2,2,2-trifluoroethanol-d₁ 
• 159562-64-8 C₁₈H₁₄F₆NO₄^(1-) 
• 159562-66-0 C₁₈H₁₇F₃NO₄S^(1-) 
• 159562-65-9 C₁₇H₁₅F₃NO₄^(1-) 
• 75-89-8 2,2,2-trifluoroethanol 
• 87191-88-6 2-oxo-ethen-1-id-1-yl 

Downstream Products

• 75-89-8 2,2,2-trifluoroethanol 
• 41084-91-7 deprotonated ketene anion 
• 460-43-5 2,2,2-trifluoroethyl methyl ether 
• 80054-70-2 2,2,2-trifluoroethyl-O-trityl eher 
• 100-02-7 4-nitro-phenol 
• 141516-55-4 2,2,2-trifluoroethyl 4-nitrobenzenesulfonate 
• 110-86-1 pyridine 
• 108-89-4 picoline 
• 150723-09-4 1-[Bis-(2,2,2-trifluoro-ethoxy)-methyl]-4-methoxy-benzene 
• 150723-10-7 1-Methoxy-4-[(2,2,2-trifluoro-ethoxy)-(2,2,2-trifluoro-ethylsulfanyl)-methyl]-benzene 
• 159562-65-9 C₁₇H₁₅F₃NO₄^(1-) 
• 159562-64-8 C₁₈H₁₄F₆NO₄^(1-) 
• 1163712-01-3 C₇H₈P^(1-) 
• 406-95-1 2,2,2-trifluoroethyl acetate 

Relevant articles and documents

Reactivity of the radical anion OCC-

The characteristic reactivity of the radical anion OCC- has been investigated in the gas phase at 298 K through determination of rate coefficients, products, and branching fractions for each of 29 ion-molecule reactions. A wide variety of reactions is observed including abstraction of H, H+, and H2+, nucleophilic displacement, charge transfer, and reactions involving electron detachment. Many of the reactions involve cleavage of the C--CO bond, consistent with the relatively small C--CO bond energy and the proposed1 electronic structure of the ground state anion in which both radical and charge are centered on the terminal carbon. Similarities are noted between the chemistry of OCC- and its neutral analogue OCC and between the chemistry of OCC- and the radical anions O- and o-C6H4-. Most reaction products observed are consistent with reaction mechanisms involving initial attack of the terminal carbon in OCC- on the neutral reaction partner. The gas-phase acidity of HCCO is bracketed between those of CH3NO2 and CH3CHO, yielding 1502 ± 8 > ΔGoacid(HCCO) ≥ 1463 ± 8 kJ mol-1 and 1531 ± 12 > ΔHoacid(HCCO) ≥ 1491 ± 12 kJ mol-1. Observation of H atom transfer from CH2Cl2 to OCC- indicates that ΔHof(OCC-) ≥ 148 ± 12 kJ mol-1 and gives a larger lower limit of ΔHoacid ≥ 1507 ± 15 kJ mol-1. These and related thermochemical values, including the hydrogen bond dissociation energy in HCCO, are compared with literature values.

Kinetic analysis of elementary steps in nucleophilic vinylic substitution reactions of α-nitro-β-X-stilbenes (X = OCH2CF3, OCH3, NO2) with various nucleophiles.

Rate constants of elementary steps in the addition-elimination mechanism of nucleophilic vinylic substitutions (SNV) were determined by studying the following reactions in 50% Me2SO-50% water at 20 °C: (1) α-nitro-β-(2,2,2-trifluoroethoxy)stilb