460-43-5Relevant articles and documents
Solvolysis in 2,2,2-Trifluoroethanol-Water and 2,2,2-Trifluoroethanol-Etanol Mixtures. Selectivity of the Intermediates and N Values
Kaspi, Joseph,Rappoport, Zvi
, p. 3829 - 3837 (1980)
Solvolysis of 1-adamantyl bromide (1-Br) in eight TFE-EtOH mixtures gave a Grunwald-Winstein mGW value of 1.50, and the ethyl (1-OEt) and trifluoroethyl (1-OTFE) ethers.The selectivity ratios for reaction with the solvent components kTFE/kEtOH are medium dependent, being 2.60-0.83.In TFE-H2O, mGW = 0.56 and the kTFE/KH2O ratios increase with ΧH2O from 0.49 to 2.04.Solvolysis of 1-anisyl-2-methylpropen-1-yl tosylate (2-OTs) in TFE-EtOH gives mGW = 0.89 and an average kTFE/kEtOH value of 0.086.Methyl tosylate was solvolyzed in several TFE-EtOH and TFE- H2O mixtures and new values of the nucleophilic parameter N were determined.Products were derived from the free cation in the solvolysis of 2-OTs and from the solvent-separated ion pair in the solvolysis of 1-Br, and the selectivities of these species were analyzed.The nucleophilicities of TFE-H2O and TFE-EtOH mixtures and the recent use of the comparison od TFE-H2O and EtOH-H2O mixtures for evaluating solvent participation in solvolysis reactions were discussed.
Preparation of Methyl Fluoroalkyl Ethers
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Page/Page column 4, (2010/12/29)
Methyl fluoroalkyl ether can be produced by the reaction of a fluoroalkyl alcohol with chloromethane. The process involves reacting an alkoxide of a fluoroalkyl alcohol with chloromethane.
Methyl hypofluorite (MeOF) reactions with various fluoroolefins
Suzuta, Tetsuya,Abe, Takashi,Sekiya, Akira
, p. 3 - 8 (2007/10/03)
The reaction of methyl hypofluorite (MeOF) with certain fluoroolefins, such as CF2=CF2, CF2=CFCF3, CF2=CFOCF3, CF2=CFOMe, CF2=CClF, CF2=CHF, CF2=CH2, CHF=CH2, CF2=CFCF=CF2, occurred in CD3CN or in the presence of NaF. Using neat MeOF in the presence of NaF was a novel method and gave good results. We observed that when more than three fluorine atoms are bonded to the C-C double bond, the addition products were obtained in mostly good yields.