24281-43-4

Basic information

• Product Name: Sulfurous acid bis(2-phenylethyl) ester
• Synonyms: Sulfurous acid bis(2-phenylethyl) ester
• CAS NO: 24281-43-4
• Molecular Formula: C₁₆H₁₈O₃S
• Molecular Weight: 290.3773
• Mol File: 24281-43-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 429°Cat760mmHg
• Flash Point: 213.3°C
• Appearance: /
• Density: 1.219g/cm³
• Vapor Pressure: 3.63E-07mmHg at 25°C
• Refractive Index: 1.603
• CAS DataBase Reference: Sulfurous acid bis(2-phenylethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: Sulfurous acid bis(2-phenylethyl) ester(24281-43-4)
• EPA Substance Registry System: Sulfurous acid bis(2-phenylethyl) ester(24281-43-4)

Safety Data

• Hazardous Substances Data: 24281-43-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H18O3S/c17-20(18-13-11-15-7-3-1-4-8-15)19-14-12-16-9-5-2-6-10-16/h1-10H,11-14H2

Upstream product

• 110-86-1 pyridine 
• 7719-09-7 thionyl chloride 
• 60-29-7 diethyl ether 
• 60-12-8 2-phenylethanol 

Downstream Products

• 474801-75-7 C₃₅H₅₀N₄O₁₃ 
• 474801-43-9 (2S,4S,5S,6R)-5-Acetylamino-4-(tert-butyl-dimethyl-silanyloxy)-6-[(S)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-phenethyloxy-methyl]-2-methoxy-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 474801-60-0 (4S,5R,6R)-5-Acetylamino-4-azido-6-((1S,2R)-2,3-diacetoxy-1-phenethyloxy-propyl)-5,6-dihydro-4H-pyran-2-carboxylic acid methyl ester 
• 138337-18-5 bis(2-phenylethyl) sulfate 
• 2396-53-4 di(2-phenylethyl) ether 

Relevant articles and documents

Synthesis and anti-influenza virus activity of 7-O-alkylated derivatives related to zanamivir

A series of 7-alkyl ether derivatives related to zanamivir were synthesized using direct alkylation of the C-7 alcohol of sialic acid. Alkyl ether moiety of less than 12 carbons in length showed low nanomolar inhibitory activity against influenza A virus sialidase. Furthermore, their moiety improved influenza A virus plaque reduction activity compared to zanamivir. However, removal of the 8,9-diol of the 7-O-alkyl derivatives resulted in loss of antiviral potency. This result suggests that 8,9-diol must play an important role in binding with both influenza A and B virus sialidases.