24307-72-0Relevant articles and documents
An Improved Synthesis of 5-Halopyrimidines: Reaction of α-Halo Ketones with Nitriles
Martinez, A. Garcia,Fernandez, A. Herrera,Vilchez, Dolores Molero,Hanack, M.,Subramanian, L. R.
, p. 1053 - 1054 (2007/10/02)
The reaction of alkyl and aryl α-halomethyl ketones 1 with aliphatic and aromatic nitriles 2 in the presence of trifluoromethanesulfonic anhydride affords substituted 5-halopyrimidines 3 in good yields (55-91percent).