24362-84-3

Basic information

• Product Name: 2-methoxyphenyl 2-methyl-2-propyl sulfide
• Synonyms: 2-methoxyphenyl 2-methyl-2-propyl sulfide
• CAS NO: 24362-84-3
• Molecular Weight: 196.313
• Mol File: 24362-84-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-methoxyphenyl 2-methyl-2-propyl sulfide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxyphenyl 2-methyl-2-propyl sulfide(24362-84-3)
• EPA Substance Registry System: 2-methoxyphenyl 2-methyl-2-propyl sulfide(24362-84-3)

Safety Data

• Hazardous Substances Data: 24362-84-3(Hazardous Substances Data)

Upstream product

• 578-57-4 2-bromoanisole 
• 75-66-1 2-methylpropan-2-thiol 
• 34232-14-9 tert-Butyl-(2-methoxy-phenyl)-sulfon 
• 7217-59-6 2-Methoxybenzenethiol 
• 115-11-7 isobutene 
• 75-65-0 tert-butyl alcohol 
• 110-06-5 di-tert-butyl disulfide 
• 100-66-3 methoxybenzene 

Downstream Products

• 91902-74-8 1-methoxy-2-(phenylsulfinyl)benzene 
• 100-84-5 1-methoxy-3-methyl-benzene 
• 155496-74-5 1-Methoxy-3-methyl-2-(2-methyl-propane-2-sulfonyl)-benzene 
• 86-26-0 2-methoxy-1,1'-biphenyl 
• 34232-14-9 tert-Butyl-(2-methoxy-phenyl)-sulfon 

Relevant articles and documents

Tert-Butyl Sulfoxides: Key Precursors for Palladium-Catalyzed Arylation of Sulfenate Salts

The present report describes an efficient and clean generation of sulfenate salts (R1SO-) by pyrolysis of readily available tert-butyl sulfoxides to give sulfenic acids (R1SOH) and traceless isobutene, followed by hydrogen abstraction with a weak inorganic base (K3PO4). The relevance of this process was exemplified through an in situ palladium-catalyzed cross-coupling reaction with aryl halides/triflates leading to aryl sulfoxides. The operationally simple C-S bond-forming protocol developed uses Pd(dba)2 as catalyst and Xantphos as ligand in toluene or a toluene/H2O mixture. Further extensions include the use of di-tert-butyl sulfoxide as an equivalent for sulfur monoxide dianion (SO2-) and the development of diastereoselective versions in the [2.2]paracyclophane and biaryl series.

Facile preparation of aryl sulfides using palladium catalysis under mild conditions

A convenient method for C-S cross-coupling of aryl bromides with various thiols has been developed that involves the use of a 1,1′- bis(diphenylphosphino)ferrocene (DPPF)-ligated palladium complex with N,N-diisopropylethylamine (DIPEA) as the base. This coupling is tolerant of a wide range of functional groups, including hydroxy, amino, cyano, nitro, formyl, and carboxyl groups. Georg Thieme Verlag Stuttgart - New York.

Oxidation of Alkylthio Substituted Tricarbonyl(η6-arene)chromium(0) Complexes to Alkylsulfinyl Substituted Tricarbonyl(η6-arene)chromium(0) Complexes

Dimethyldioxirane efficiently oxidises tricarbonylchromium(0) complexes of alkylthio substituted arenes to tricarbonylchromium(0) complexes of alkylsulfinyl substituted arenes.The diastereoselectivity of oxidation of ortho substituted complexes, which was determined by inter alia X-ray crystal structure analyses of tricarbonyl6-1-methoxy-2-(methylsulfinyl)benzene>-chromium(0) 20x, 6-1-(tert-butylsulfinyl)-2-methoxybenzene>tricarbonylchromium(0) 23x and tricarbonyl6-1-(ethylsulfinyl)-2-methoxybenzene)chromium(0) 21y, is dependent on the alkylthio substituent and is reversed when this substituent is changed from methylthio to tert-butylthio.