2458-24-4

Basic information

• Product Name: ethyl (2Z)-2-cyano-3-[(4-nitrophenyl)amino]prop-2-enoate
• CAS NO: 2458-24-4
• Molecular Formula: C₁₂H₁₁N₃O₄
• Molecular Weight: 261.2334
• Mol File: 2458-24-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 424.5°C at 760 mmHg
• Flash Point: 210.5°C
• Density: 1.349g/cm³
• Vapor Pressure: 2.06E-07mmHg at 25°C
• Refractive Index: 1.61
• CAS DataBase Reference: ethyl (2Z)-2-cyano-3-[(4-nitrophenyl)amino]prop-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (2Z)-2-cyano-3-[(4-nitrophenyl)amino]prop-2-enoate(2458-24-4)
• EPA Substance Registry System: ethyl (2Z)-2-cyano-3-[(4-nitrophenyl)amino]prop-2-enoate(2458-24-4)

Safety Data

• Hazardous Substances Data: 2458-24-4(Hazardous Substances Data)

Upstream product

• 100-01-6 4-nitro-aniline 
• 94-05-3 ethyl (ethoxymethylene)cyanoacetate 
• 1205-59-0 N₁,N₁-dimethyl-N₂-(4-nitro-phenyl)-formamidine 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 214484-15-8 N-[4-[(3-bromophenyl)amino]-3-cyano-6-quinolinyl]-2-propenamide 
• 214485-09-3 4-[(3-chloro-4-fluorophenyl)amino]-6-nitro-quinoline-3-carbonitrile 
• 214485-08-2 6-Amino-4-[(3-chloro-4-fluorophenyl)amino]-quinoline-3-carbonitrile 
• 214484-09-0 4-[(3-bromophenyl)amino]-6-nitro-quinoline-3-carbonitrile 
• 214484-11-4 6-amino-4-[(3-bromophenyl)-amino]-3-quinolinecarbonitrile 
• 214470-37-8 4-chloro-6-nitro-3-quinolinecarbonitrile 
• 214485-06-0 N-{4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-6-quinolinyl}-4-morpholino-2-butenamide 
• 214485-37-7 N-{4-[(3-bromo-4-fluorophenyl)amino]-3-cyano-6-quinolinyl}-4-morpholino-2-butenamide 
• 214485-16-2 N-{4-[(3-chloro-4-thiophenoxyphenyl)amino]-3-cyano-6-quinolinyl}-2-butynamide 
• 214485-05-9 N-{4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-6-quinolinyl}-4-diethylamino-2-butenamide 
• 214486-84-7 N-{4-[(3-chloro-4-thiophenoxyphenyl)amino]-3-cyano-6-quinolinyl}-2-propenamide 
• 214484-72-7 4-diethylamino-but-2-enoic acid [4-(3-bromophenylamino)-3-cyano-quinolin-6-yl]-amide 
• 214484-73-8 4-methylamino-but-2-enoic acid [4-(3-bromophenylamino)-3-cyano-quinolin-6-yl]-amide 
• 214484-71-6 4-dimethylamino-but-2-enoic acid [4-(3-bromophenylamino)-3-cyano-quinolin-6-yl]-amide 

Relevant articles and documents

Substituted 3-cyanoquinolines as protein tyrosine kinases inhibitors

This invention provides compounds of formula 1 wherein R1, G1, G2, R4, Z, X and n are defined herein, or a pharmaceutically acceptable salt thereof, which are useful as antineoplastic agents and in the treatment of polycystic kidney disease.

Esters of the 3-arylamino-2-cyanoacrylic acid

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