24821-17-8 Usage
Description
2-AMINO-3-NITROBENZOTRIFLUORIDE is an organic compound with the molecular formula C7H5F3N2O2. It is a synthetic chemical intermediate that possesses a nitro group and an amino group attached to a benzene ring, with three fluorine atoms attached to the carbon atoms. 2-AMINO-3-NITROBENZOTRIFLUORIDE is known for its reactivity and is commonly used in the synthesis of various pharmaceuticals and chemical products.
Uses
Used in Pharmaceutical Industry:
2-AMINO-3-NITROBENZOTRIFLUORIDE is used as a key intermediate for the synthesis of benzimidazoles, which are important compounds in the development of various pharmaceuticals. It is used in the reductive heterocyclization with orthoesters using indium, allowing for the creation of benzimidazoles with potential applications in drug discovery and medicinal chemistry.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-AMINO-3-NITROBENZOTRIFLUORIDE is utilized as a versatile reactant for the one-pot preparation of quinoxalines. This is achieved through reductive coupling with 1,2-diketones using indium. Quinoxalines are valuable compounds with a wide range of applications, including their use as building blocks in the synthesis of complex organic molecules and as active pharmaceutical ingredients.
Overall, 2-AMINO-3-NITROBENZOTRIFLUORIDE is a significant compound in the pharmaceutical and chemical industries due to its role in the synthesis of various important molecules and its potential for further research and development in drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 24821-17-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,8,2 and 1 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 24821-17:
(7*2)+(6*4)+(5*8)+(4*2)+(3*1)+(2*1)+(1*7)=98
98 % 10 = 8
So 24821-17-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H5F3N2O2/c8-7(9,10)4-2-1-3-5(6(4)11)12(13)14/h1-3H,11H2
24821-17-8Relevant articles and documents
TREATING LONG QT SYNDROME
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Page/Page column 33, (2020/08/22)
This document relates to compounds useful for treating and preventing disorders associated with long QT syndrome such as cardiac arrhythmia, ventricular arrhythmia, hypertrophic cardiomyopathy, and congestive heart failure. Also provided herein are methods and materials for using such compounds to shorten myocardial repolarization time in a patient.
Copper-catalyzed direct amination of nitrobenzenes with O-alkylhydroxylamines
Seko, Shinzo,Kawamura, Norio
, p. 442 - 443 (2007/10/02)
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Quinoxaline derivatives as immune regulants
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, (2008/06/13)
Novel quinoxaline derivatives, useful as immune regulatory agents capable of altering the immune response in mammals.
