250650-58-9Relevant articles and documents
Oxidative deprotection of diphenylmethylamines
Sampson, Peter B.,Honek, John F.
, p. 1395 - 1397 (2008/02/09)
(formula presented) The diphenylmethyl amino protecting group can be efficiently removed by initial oxidation of the amine to an imine by 2,3-dichloro-5,6-dicyanobenzoquinone. The resulting imine can then be easily hydrolyzed under mildly acidic conditions. This method is particularly well suited for the preparation of α-amino phosphinates and α-amino phosphonates.