2523-44-6 Usage
Description
2-Chlorofluorene, also known as 2-chloro-9H-fluorene, is an organic compound that features a chlorine atom attached to a fluorene backbone. It is a versatile intermediate in organic synthesis and possesses unique chemical properties due to the presence of the chlorine atom, which can be further functionalized or utilized in various chemical reactions.
Uses
Used in Organic Synthesis:
2-Chlorofluorene is used as a reagent for the synthesis of various organic compounds. Its chlorine atom can be replaced or functionalized to form a wide range of derivatives, making it a valuable building block in the creation of complex organic molecules.
Used in Pharmaceutical Industry:
2-Chlorofluorene is used as a key intermediate in the synthesis of pharmaceutical compounds. Its unique structure and reactivity allow for the development of new drugs with potential therapeutic applications.
Used in Chemical Research:
2-Chlorofluorene is utilized in chemical research to study the properties and reactions of halogenated aromatic compounds. It serves as a model compound for understanding the behavior of chlorine-containing molecules in various chemical processes.
Used in Antibacterial Applications:
2-Chlorofluorene is used as a reagent for the synthesis of N-alkyl and N-amylamidinohydrazones of acetophanones, benzophenones, and 2-acylfluorenes, which exhibit antibacterial functions. These compounds can be further optimized and developed into potential antibacterial agents for treating infections caused by various pathogens.
Check Digit Verification of cas no
The CAS Registry Mumber 2523-44-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,2 and 3 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2523-44:
(6*2)+(5*5)+(4*2)+(3*3)+(2*4)+(1*4)=66
66 % 10 = 6
So 2523-44-6 is a valid CAS Registry Number.
InChI:InChI=1/C13H9Cl/c14-11-5-6-13-10(8-11)7-9-3-1-2-4-12(9)13/h1-6,8H,7H2
2523-44-6Relevant articles and documents
-
Streitwieser
, p. 2127 (1944)
-
-
Buffle
, p. 1483 (1932)
-
Solid-state construction of zigzag periphery: Via intramolecular C-H insertion induced by alumina-mediated C-F activation
Akhmetov, Vladimir,Amsharov, Konstantin,F?rtsch, Andreas,Feofanov, Mikhail
, p. 12325 - 12328 (2021/11/30)
Caryl-F bond activation has become an important and quickly developing method for construction of carbon-based materials. We report that alumina-mediated C-F bond activation (AmCFA) enables construction of PAHs with zigzag periphery. This method includes
Palladium-Catalyzed Formal [4 + 1] Annulation via Metal Carbene Migratory Insertion and C(sp2)-H Bond Functionalization
Xu, Shuai,Chen, Ri,Fu, Zihao,Zhou, Qi,Zhang, Yan,Wang, Jianbo
, p. 1993 - 1997 (2017/08/14)
A highly efficient and operationally simple palladium-catalyzed formal [4 + 1] annulation reaction has been developed. The reaction is featured by the formation of two different C-C bonds on a carbenic center. It represents a concise method for the synthesis of a wide range of polycyclic aromatic hydrocarbons (PAHs) and 1H-indenes with easily available (trimethylsilyl)diazomethane as the carbene source. Metal carbene migratory insertion and C(sp2)-H bond activation are proposed as the key steps in this transformation. The reaction further demonstrates the versatility of the carbene-based coupling in combination with various transition-metal-catalyzed transformations.