25365-87-1

Basic information

• Product Name: 1H-Isoindole, 3-ethoxy-1-phenyl-
• CAS NO: 25365-87-1
• Molecular Formula: C16H15NO
• Molecular Weight: 237.301
• Mol File: 25365-87-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole, 3-ethoxy-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole, 3-ethoxy-1-phenyl-(25365-87-1)
• EPA Substance Registry System: 1H-Isoindole, 3-ethoxy-1-phenyl-(25365-87-1)

Safety Data

• Hazardous Substances Data: 25365-87-1(Hazardous Substances Data)

Upstream product

• 85-52-9 2-Benzoylbenzoic acid 
• 136918-14-4 phthalimide 
• 30696-82-3 3-Chlor-isoindolin-1-on 
• 19298-29-4 4-phenyl-1H-benzo[d][1,2]oxazin-1-one 
• 100-47-0 benzonitrile 
• 35822-58-3 2-bromobenzaldehyde diethyl acetal 
• 26486-93-1 3-hydroxy-2,3-dihydro-isoindol-1-one 
• 368-39-8 triethyloxonium fluoroborate 
• 835-18-7 3-phenyl-2,3-dihydro-isoindol-1-one 

Downstream Products

• 917776-93-3 C₁₇H₁₇NO 

Relevant articles and documents

A facile synthesis of 1-substituted 3-alkoxy-1h-isoindoles based on the reaction of 2-(dialkoxymethyl)phenyllithiums with nitriles, followed by acid-catalyzed cyclization

A two-step synthesis of 1-substituted 3-alkoxy-1H-isoindoles 4 has been developed. Thus, the reaction of 2-(dialkoxymethyl)phenyllithium compounds, which are easily generated in situ by Br/Li exchange between 1-bromo-2-(dialkoxymethyl)benzenes 1 and BuLi

Untersuchungen zur Chemie von Isoindolen und Isoindoleninen, XXXVIII. 3-Alkoxy-1H-isoindole mit Substituenten am 5-Ring - Heterocycliche Imidsaeureester mit fixierter benzoider Struktur.

3-Alkoxy-1H-isoindoles bearing substituents at the five-membered ring have been synthesized starting with substituted isoindoline-1-ones via regiospecific O-alkylation with trialkyl oxonium tetrafluoroborates or alkyl trifluoromethanesulfonates and subsequent NH-deprotonation.The dependence of spectroscopic properties on the substituents has been investigated.The heterocyclic imidates exist exclusively in the benzenoid 1H-structure; the tautomeric o-quinonoid 2H-form cannot be detected by spectroscopic means.