253867-10-6Relevant articles and documents
Stereoselective synthesis of (2S,7S)-7-(4-phenoxymethyl)-2-(1-N- hydroxyureidyl-3-butyn-4-yl)oxepane: A potential anti-asthmatic drug candidate
Gurjar, Mukund K.,Rao, B. Venkateswara,Krishna, L. Murali,Chorghade, Mukund S.,Ley, Steven V.
, p. 935 - 939 (2005)
We have achieved a short, efficient stereoselective synthesis of 7-membered oxepane derivatives with potential against asthma. Highlights of our synthetic strategy are regioselective oxidation of a hydroxyl group and efficient ring closure of an open chai