25631-82-7

Basic information

• Product Name: 4-phenyl-2H-pyran-2,6(3H)-dione
• Synonyms: 4-phenyl-2H-pyran-2,6(3H)-dione
• CAS NO: 25631-82-7
• Molecular Weight: 188.183
• Mol File: 25631-82-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4-phenyl-2H-pyran-2,6(3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 4-phenyl-2H-pyran-2,6(3H)-dione(25631-82-7)
• EPA Substance Registry System: 4-phenyl-2H-pyran-2,6(3H)-dione(25631-82-7)

Safety Data

• Hazardous Substances Data: 25631-82-7(Hazardous Substances Data)

Upstream product

• 87894-68-6 3-phenylpent-2-enedioic acid 
• 93-89-0 benzoic acid ethyl ester 
• 124-38-9 carbon dioxide 
• 704-80-3 (E)-3-phenyl-2-butenoic acid 
• 68204-17-1 3-phenylbut-2-enoyl chloride 
• 133900-69-3 6-Methyl-2-oxo-3-phenyl-2H-pyran-5-carbonsaeureethylester 
• 117726-46-2 3-hydroxy-3-phenyl-pentanedioic acid 
• 38400-77-0 diallyl carbinol 

Downstream Products

• 117726-56-4 6-Methoxy-4-phenyl-pyran-2-one 
• 1610724-52-1 (2R,3R)-1'-tert-butyl 3-ethyl 1,2'-dioxo-5-phenylspiro[cyclohex[5]ene-2,3'-indoline]-1',3-dicarboxylate 
• 4160-80-9 3-phenylglutaric acid anhydride 
• 98606-70-3 Dimethyl 2-phenyl-1,3-propenedicarboxylate 

Relevant articles and documents

Further Insight into the Castagnoli-Cushman-type Synthesis of 1,4,6-Trisubstituted 1,6-Dihydropyridin-2-(3 H)-ones from 3-Arylglutaconic Acid Anhydrides

The earlier reported three-component Castagnoli-Cushman-type synthesis of 1,4,6-trisubstituted 1,6-dihydropyridin-2-(3H)-ones from 3-arylglutaconic acids, primary amines, and aromatic aldehydes has been further investigated. It was shown to proceed via 3-arylglutaconic anhydrides, which, in turn, were found to give superior results in the two-component reactions with imines. The initial formation of the Castagnoli-Cushman carboxylic acids was shown to be the case, and their decarboxylation was found to follow a complex, forked pathway, which was confirmed by deuterium incorporation experiments.

Carboxylative Cyclization of 2-Butenoates with Carbon Dioxide: Access to Glutaconic Anhydrides

Cyclic anhydrides are versatile synthons and functional comonomers. Herein, we reported an organic base-promoted carboxylative cyclization of 2-butenoates with carbon dioxide to produce important glutaconic anhydrides in good yields. This metal-free react

Catalytic asymmetric tamura cycloadditions

In the presence of a novel, tert-butyl-substituted squaramide-based catalyst, enolizable anhydrides react with alkylidene oxindoles to generate spirooxindole products of significant synthetic interest with excellent enantio- and diastereocontrol. The methodology is of wide scope and encompasses both homophthalic and glutaconic anhydride derivatives, which lead to structurally diverse products. Glutaconic acid-derived anhydrides undergo a clean post-cyclization decarboxylation process which is not a feature of reactions involving homophthalic acid-derived anhydrides. The unusual influence of reaction temperature on diastereocontrol has been probed, with reactions occurring at 30 °C and -30 °C delivering products epimeric at one stereocenter only, in near optical purity. Squared away: The first strategy for bringing about enantioselective Tamura reactions is reported. In the presence of a squaramide-based catalyst, enolizable anhydrides react with alkylidene oxindoles to generate spirooxindole products with excellent enantio- and diastereocontrol. The methodology is of wide scope and leads to structurally diverse products.