25632-70-6

Basic information

• Product Name: 5-Oxo-3,4-diphenyl-4,5-dihydroisoxazol
• Synonyms: 5-Oxo-3,4-diphenyl-4,5-dihydroisoxazol
• CAS NO: 25632-70-6
• Molecular Weight: 237.258
• Mol File: 25632-70-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 5-Oxo-3,4-diphenyl-4,5-dihydroisoxazol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Oxo-3,4-diphenyl-4,5-dihydroisoxazol(25632-70-6)
• EPA Substance Registry System: 5-Oxo-3,4-diphenyl-4,5-dihydroisoxazol(25632-70-6)

Safety Data

• Hazardous Substances Data: 25632-70-6(Hazardous Substances Data)

Upstream product

• 32569-84-9 ethoxyethynylbenzene 
• 65-85-0 benzoic acid 
• 58929-02-5 ethyl 2,3-diphenyl-3-oxopropanoate 
• 451-40-1 phenyl benzyl ketone 
• 53983-66-7 N-hydroxy-3-hydroxyamino-2,3-diphenyl-propionamidine 
• 698-16-8 benzohydroximoyl chloride 
• 101-41-7 benzeneacetic acid methyl ester 
• 52392-73-1 5-amino-3,4-diphenylisoxazole 

Downstream Products

• 181696-10-6 4-[5-trifluoromethanesulfonoxy-3-phenylisoxazol-4-yl]benzenesulfonamide 
• 181695-83-0 4-[5-hydroxy-3-phenyl-4-isoxazolyl]benzenesulfonamide 
• 181696-09-3 4-[5-chloro-3-phenylisoxazol-4-yl]benzenesulfonamide 
• 1361387-05-4 methyl 2,3-diphenyl-2H-azirine-2-carboxylate 
• 1352634-56-0 4-(2-methylallyl)-3,4-diphenyl-4H-isoxazol-5-one 
• 1352634-83-3 C₁₉H₁₇NO₂ 
• 78371-22-9 2,2-dimethyl-4,5-diphenyl-3,4-dihydro-2H-pyrrole 
• 1352634-65-1 2,3-diphenyl-5-methyl-1-azabicyclo[3.1.0]hex-2-ene 
• 181696-90-2 C₁₅H₁₀ClNO₄S 
• 63955-24-8 formic acid N'-(3,4-diphenyl-isoxazol-5-yl)-N,N'-dimethyl-hydrazide 

Relevant articles and documents

One-Pot Reaction of Carboxylic Acids and Ynol Ethers for the Synthesis of β-Keto Esters

An one-pot reaction of carboxylic acids and ynol ethers for the synthesis of β-keto esters has been developed. Under promotion of Ag2O, various carboxylic acids and ynol ethers could transform to α-acyloxy enol esters, which undergo a following DMAP-catalyzed rearrangement to deliver β-keto esters rapidly. This method provides a direct approach to β-keto esters from carboxylic acids without any preactivation. The protocol features mild reaction conditions, broad substrate scope, and the products could be transformed to an array of compounds.

Atom-Economic Silver-Catalyzed Difunctionalization of the Isocyano Group with Cyclic Oximes: Towards Pyrimidinediones

An unprecedented silver-catalyzed difunctionalization of the isocyano group with cyclic oximes is described. This method allows efficient and atom-economic assembly of a vast array of structurally novel and interesting pyrimidinediones, and tolerates a range of functionalities. The resulting products can be easily converted into some useful compounds. Furthermore, the method can also be applied for the late-stage modification of a few biologically active molecules.

Palladium-catalyzed decarboxylative intramolecular aziridination from 4h-isoxazol-5-ones leading to 1-azabicyclo[3.1.0]hex-2-enes

A decarboxylative intramolecular aziridination reaction of alkene-tethered 4H-isoxazol-5-ones with a palladium/phosphine catalyst gave 1-azabicyclo[3.1.0] hex-2-enes in moderate to high yields (see scheme; dba=dibenzylideneacetone). The resulting N-fused bicyclic aziridines readily reacted with various reagents to afford ring-opening pyrroline derivatives.