257-07-8Relevant articles and documents
Microwave assisted synthesis of dibenzoxazepines
Ghafarzadeh, Mohammad,Moghadam, Ebrahim Saeedian,Faraji, Fereshteh
, p. 754 - 757 (2013)
Dibenzo[b,f][1,4]oxazepine derivatives were synthesized in good yields and short reaction times by the reaction of 2-chlorobenzaldehydes and 2-aminophenoles in basic conditions under microwave irradiation. Copyright
Dibenz[b,e]azepines. Part 3. Acid hydrolysis
Noskov,Kalinina,Noskova,Kruglyak,Bezrukov,Strukov,Kurochkin
, p. 619 - 620 (1998)
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Improved etherification procedure for the preparation of dibenz[b,f][1,4]oxazepine
Fakhraian,Nafary,Yarahmadi,Hadj-Ghanbary
, p. 1469 - 1471 (2008)
(Chemical Equation Presented) The effect of temperature and catalyst on the yield and rate of the etherification reaction between 1 and 2 was investigated and alternative methods for separation of 3 and 4 from the reaction mixture have been described.
Visible-Light-Induced Cycloaddition of α-Ketoacylsilanes with Imines: Facile Access to β-Lactams
Ye, Jian-Heng,Bellotti, Peter,Paulisch, Tiffany O.,Daniliuc, Constantin G.,Glorius, Frank
supporting information, p. 13671 - 13676 (2021/05/11)
We report the synthesis of β-lactams from α-ketoacylsilanes and imines, which proceeds via a formal [2+2] photochemical cycloaddition with in situ generation of siloxyketene. This mild and operationally simple reaction proceeds in an atom-economic fashion with broad substrate scope, including aldimines, ketimines, hydrazones, and fused nitrogen heterocycles, affording a variety of important β-lactams with satisfactory diastereoselectivities in most cases. This reaction also features good functional-group tolerance, facile scalability and product diversification. Experimental and computational studies suggest that α-ketoacylsilanes can serve as photochemical precursors by engaging in a 1,3 silicon shift to the distal carbonyl group.
Unlocking the direct photocatalytic difluoromethylation of CN bonds
Alemán, José,Garrido-Castro, Alberto F.,Gini, Andrea,Maestro, M. Carmen
supporting information, p. 3769 - 3772 (2020/04/10)
The current study presents a direct CF2H radical addition to CN bonds predicated on the photocatalytic activation of commercially available zinc difluoromethanesulfinate. The mild conditions in place lead to impressive structural diversity, as quinoxalinones and dibenzazepines, among others, are successfully functionalized.
Enantioselective Copper-Catalyzed Three-Component Carboboronation of Allenes: Access to Functionalized Dibenzo [b,f][1,4]oxazepine Derivatives
Deng, Hao,Meng, Ziwei,Wang, Sifan,Zhang, Zheming,Zhang, Yaqi,Shangguan, Yu,Yang, Fazhou,Yuan, Dekai,Guo, Hongchao,Zhang, Cheng
supporting information, p. 3582 - 3587 (2019/07/17)
A copper-catalyzed enantioselective three-component difunctionalization of allenes with seven-membered cyclic imines and bis(pinacolato)diboron (B2(Pin)2) to approach functionalized dibenzo[b,f][1,4]oxazepine derivatives is developed. The chiral products are obtained in up to 81% yield, >20:1 dr, and 98% ee when either a chiral diphosphine ligand or a chiral ferrocenyl-based P,N-ligand is used. Furthermore, the reaction exhibits reversed diastereoselectivities when the chiral diphosphine ligand and the chiral P,N-ligand are used respectively. (Figure presented.).