25736-86-1Relevant articles and documents
Protein-Grafted Polymers Prepared Through a Site-Specific Conjugation by Microbial Transglutaminase for an Immunosorbent Assay
Wakabayashi, Rie,Yahiro, Kensuke,Hayashi, Kounosuke,Goto, Masahiro,Kamiya, Noriho
, p. 422 - 430 (2017)
Protein-polymer conjugates have been developed in many fields. Most hybrids are composed of one protein attached to one or several polymer chains. The other form of hybrid involves the construction of multiple proteins on one polymer chain, thereby facili
Acrylate monomer having hydrophilic end group and a method for preparing the same
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Paragraph 0093-0106; 0128-0132, (2021/11/02)
More particularly, the present invention relates to an acrylate monomer having a high-purity hydrophilic terminal group which does not contain unreacted 1 water or undesirable by-products, and a method for producing the acrylate monomer. These acrylate monomers are substantially free of polymerization inhibitors. Chemical Formula 1. In Chemical Formula 1, R. 1 Chem. R. 2 Chem. R. 3 May be H, or linear, branched or cyclic C, independently of each other. 1 -C12 alkyl group. R4 Is linear, branched or cyclic C. 1 -C12 alkyl Or C1 -C12 It is alkoxy group, wherein alkyl group carbon atoms can be unsubstituted or substituted with oxygen atoms, n Is an integer selected from 1 and 10.
BIOGUM AND BOTANICAL GUM HYDROGEL BIOINKS FOR THE PHYSIOLOGICAL 3D BIOPRINTING OF TISSUE CONSTRUCTS FOR IN VITRO CULTURE AND TRANSPLANTATION
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, (2021/01/20)
Bioink compositions comprising a biomaterial (mammalian, plant based, synthetically derived, or microbially derived) such as a hydrogel and a microbial-, fungal-, or plant-produced polysaccharide, with or without cells, for use in the 3D bioprinting of human tissues and scaffolds are described. The bioink compositions have excellent printability and improved cell function, viability and engraftment. Furthermore, the bioink compositions can be supplemented through the additional of auxiliary proteins and other molecules such as growth factors including extracellular matrix components, Laminins, super affinity growth factors and morphogens. The bioink compositions can be used under physiological conditions related to 3D bioprinting parameters which are cytocompatible (e.g. temperature, printing pressure, nozzle size, bioink gelation process). The combination of a biogum-based biomaterial together with mammalian, plant, microbial or synthetically derived hydrogels exhibited improvement in printability, cell function and viability compared to tissues printed with bioink not containing biogums.
All-cell tumor nano vaccine Preparation method and application thereof
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Paragraph 0063-0065, (2021/11/21)
The invention relates to a whole-cell tumor nano vaccine and a preparation method and application thereof. The whole-cell tumor nano vaccine is a nano-vaccine of an acid-sensitive polymer-loaded immunoadjuvant, a nano-vaccine of an acid-sensitive polymer - immunologic adjuvant conjugate, a nano vaccine coated with an engineering tumor cell membrane, or a combination of the two. To the whole-cell tumor nano vaccine, dendritic cell antigen presenting efficiency can be enhanced, multiple specific cytotoxic T lymphocytes are activated, efficient anti-tumor recurrence and transfer effects are achieved, and meanwhile, personalized treatment of malignant tumors is facilitated.