26066-16-0 Usage
General Description
Benzene, 1-(chloromethyl)-3-(1-methylethoxy)- is a chemical compound that is composed of benzene as the base structure with a chloromethyl group and a methylethoxy group attached to it. The chloromethyl group consists of a chlorine atom linked to a carbon atom, and the 1-methylethoxy group consists of a methylethoxy moiety attached to the benzene ring. This chemical compound is often used as an intermediate in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. It is important to handle this compound with proper safety precautions and in accordance with established chemical handling guidelines due to its potential hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 26066-16-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,0,6 and 6 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 26066-16:
(7*2)+(6*6)+(5*0)+(4*6)+(3*6)+(2*1)+(1*6)=100
100 % 10 = 0
So 26066-16-0 is a valid CAS Registry Number.
26066-16-0Relevant articles and documents
Methyl-substitution of an iminohydantoin spiropiperidine β-secretase (BACE-1) inhibitor has a profound effect on its potency
Egbertson, Melissa,McGaughey, Georgia B.,Pitzenberger, Steven M.,Stauffer, Shaun R.,Coburn, Craig A.,Stachel, Shawn J.,Yang, Wenjin,Barrow, James C.,Neilson, Lou Anne,McWherter, Melody,Perlow, Debra,Fahr, Bruce,Munshi, Sanjeev,Allison, Timothy J.,Holloway, Katharine,Selnick, Harold G.,Yang, Zhiqiang,Swestock, John,Simon, Adam J.,Sankaranarayanan, Sethu,Colussi, Dennis,Tugusheva, Katherine,Lai, Ming-Tain,Pietrak, Beth,Haugabook, Shari,Jin, Lixia,Chen,Holahan, Marie,Stranieri-Michener, Maria,Cook, Jacquelynn J.,Vacca, Joseph,Graham, Samuel L.
, p. 4812 - 4819 (2015/10/28)
The IC50 of a beta-secretase (BACE-1) lead compound was improved ～200-fold from 11 μM to 55 nM through the addition of a single methyl group. Computational chemistry, small molecule NMR, and protein crystallography capabilities were used to com
