26460-91-3

Basic information

• Product Name: benzyl-4-hydroxy-2,2,6,6-tetramethylpiperidinyl-1-oxyl
• Synonyms: benzyl-4-hydroxy-2,2,6,6-tetramethylpiperidinyl-1-oxyl
• CAS NO: 26460-91-3
• Molecular Weight: 263.38
• Mol File: 26460-91-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: benzyl-4-hydroxy-2,2,6,6-tetramethylpiperidinyl-1-oxyl(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl-4-hydroxy-2,2,6,6-tetramethylpiperidinyl-1-oxyl(26460-91-3)
• EPA Substance Registry System: benzyl-4-hydroxy-2,2,6,6-tetramethylpiperidinyl-1-oxyl(26460-91-3)

Safety Data

• Hazardous Substances Data: 26460-91-3(Hazardous Substances Data)

Upstream product

• 103-82-2 phenylacetic acid 
• 45985-24-8 TEMPOL 
• 122-78-1 phenylacetaldehyde 
• 108-88-3 toluene 

Relevant articles and documents

Metal free decarboxylative aminoxylation of carboxylic acids using a biphasic solvent system

The smooth oxidative radical decarboxylation of carboxylic acids with TEMPO and other derivatives as radical scavengers is reported. The key to success was the use of a two-phase solvent system to avoid otherwise predominant side reactions such as the oxidation of TEMPO by persulfate and enabled the selective formation of synthetically useful alkoxyamines. The method does not require transition metals and was successfully used in a new synthetic approach for the antidepressant indatraline.

TEMPO-Mediated Oxidative Deformylation of Aldehydes: Applications in the Synthesis of Polyketide Fragments

A TEMPO-mediated oxidative deformylation of aldehydes is reported that yields the TEMPO adducts, which can be further oxidized to the corresponding ketones. The focus of this work was on the optimization of a synthetic protocol for use in natural product

The thermal reaction of sterically hindered nitroxyl radicals with allylic and benzylic substrates: Experimental and computational evidence for divergent mechanisms

The reaction of stable sterically hindered nitroxyl radicals with benzylic and allylic substrates was investigated. An allyloxyamine derivative was obtained by the reaction of 2 molar equiv of a nitroxyl radical with an unactivated alkene. Experimental an