26513-20-2

Basic information

• Product Name: 3-(N,N-DIMETHYLAMINO)ANILINE
• Synonyms: 3-(N,N-DIMETHYLAMINO)ANILINE;3-Amino-N,N-diethylaniline;N,N-Diethyl-1,3-benzenediamine;1-N,1-N-diMethylbenzene-1,3-diaMine;N1,N1-Diethylbenzene-1,3-diaMine;N1,N1-Diethyl-1,3-benzenediamine
• CAS NO: 26513-20-2
• Molecular Formula: C₁₀H₁₆N₂
• Molecular Weight: 136.19428
• Mol File: 26513-20-2.mol
• Article Data: 15

Chemical Properties

• Melting Point: 152°C
• Boiling Point: 281.73°C (rough estimate)
• Flash Point: °C
• Appearance: /
• Density: 1.0244 (rough estimate)
• Refractive Index: 1.5700 (estimate)
• Storage Temp.: 2-8°C
• PKA: 6.73±0.30(Predicted)
• CAS DataBase Reference: 3-(N,N-DIMETHYLAMINO)ANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(N,N-DIMETHYLAMINO)ANILINE(26513-20-2)
• EPA Substance Registry System: 3-(N,N-DIMETHYLAMINO)ANILINE(26513-20-2)

Safety Data

• Hazardous Substances Data: 26513-20-2(Hazardous Substances Data)

Usage

General Description

3-(N,N-Dimethylamino)aniline is a chemical compound with the molecular formula C8H12N2. It is a colorless to pale yellow liquid and is derived from aniline through the substitution of the amino group with a dimethylamino group. 3-(N,N-DIMETHYLAMINO)ANILINE is commonly used in the production of dyes, pigments, and pharmaceuticals. It is also used as a catalyst in certain chemical reactions and as an intermediate in the synthesis of various organic compounds. However,

InChI:InChI=1/C10H12N2O2/c1-8(13)12-11-7-9-5-3-4-6-10(9)14-2/h3-7H,1-2H3,(H,12,13)

Upstream product

• 19372-80-6 2-chloro-N,N-diethylaniline 
• 91-66-7 N,N-diethylaniline 
• 99-09-2 3-nitro-aniline 
• 6375-46-8 m-acetylamino-N,N-diethylanilne 
• 2216-16-2 N,N-diethyl-3-nitroaniline 
• 108-37-2 1-bromo-3-chlorobenzene 

Downstream Products

• 20246-81-5 4,4'-dinitrodiphenic acid 
• 22185-75-7 N,N-diethyl-N'-propionyl-1,3-benzenediamine 
• 76751-15-0 3-Valeramido-N,N-diethyl-anilin 
• 33065-03-1 C₁₆H₂₀N₂O₂S 
• 870274-40-1 C₁₅H₁₉N₃O₂S 

Relevant articles and documents

Design, synthesis, and photophysical characterization of novel pentacyclic red shifted azine dyes

As part of our continuing efforts to develop second generation photodynamic therapeutic agents [1], we synthesized three pentacyclic azine dyes that were designed with the aid of MNDO calculations to absorb visible light having wavelengths longer than 600

Synthesis of novel reactive disperse silicon-containing dyes and their coloring properties on silicone rubbers

Novel red and purple reactive disperse silicon-containing dyes were designed and synthesized using p-nitroaniline and 6-bromo-2,4-dinitro-aniline as diazonium components, the first condensation product of cyanuric chloride and 3-(N,N-diethyl)amino-aniline

Inter-alkane amidogen phenolic synthetic method (by machine translation)

Inter-alkane amidogen phenolic synthetic method, its characteristic is: 1st step, between the two alkane amidogen acyl aniline and sulfuric acid aqueous solution mixing and heating to 50 - 110 °C, thermal insulation reaction of aniline [...] sulfuric acid aqueous solution; 2nd step, continue to drip the sodium nitrite aqueous solution, sodium nitrite aqueous solution for dropping temperature of - 10 - 20 °C, drop bi yu 5 - 30 °C insulation, [...] aniline obtained diazonium salt of the sulfuric acid aqueous solution; 3rd step, [...] aniline diazonium salt of the sulfuric acid aqueous solution is directly heated to 45 - 110 °C, thermal insulation, in the hydrolysis reaction of the diazonium salt, cooling after treatment, to obtain the product between two alkane amidogen phenol; three-step required by the reaction of sulfuric acid in the 1st step reaction in the finished disposable adding; a three-step reaction in a finish step by step in the pot. The method of the invention with raw materials are cheap, abundant, synthetic high security of the process, the product yield is high, the three waste less pollution and the like, has high industrial value. (by machine translation)

Catalyst-Directed Chemoselective Double Amination of Bromo-chloro(hetero)arenes: A Synthetic Route toward Advanced Amino-aniline Intermediates

A chemoselective sequential one-pot coupling protocol was developed for preparing several amino-anilines in high yield as building blocks for active pharmaceutical ingredients (APIs). Site (Cl vs Br on electrophile) and nucleophile (amine vs imine) selectivity is dictated by the catalyst employed. A Pd-crotyl(t-BuXPhos) precatalyst selectively coupled the Ar-Br of the polyhaloarene with benzophenone imine, even in the presence of a secondary amine, while Pd-based RuPhos or (BINAP)Pd(allyl)Cl coupled the Ar-Cl site with secondary amines.