26786-28-7

Basic information

• Product Name: 5-bromo-2-phenylpyrimidin-4-ol
• Synonyms: 5-bromo-2-phenylpyrimidin-4-ol
• CAS NO: 26786-28-7
• Molecular Formula: C₁₀H₇BrN₂O
• Molecular Weight: 251
• Mol File: 26786-28-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 250-252 °C
• Appearance: /
• Density: 1.61±0.1 g/cm3(Predicted)
• PKA: 6.68±0.50(Predicted)
• CAS DataBase Reference: 5-bromo-2-phenylpyrimidin-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-2-phenylpyrimidin-4-ol(26786-28-7)
• EPA Substance Registry System: 5-bromo-2-phenylpyrimidin-4-ol(26786-28-7)

Safety Data

• Hazardous Substances Data: 26786-28-7(Hazardous Substances Data)

Usage

General Description

5-bromo-2-phenylpyrimidin-4-ol is a chemical compound with a molecular formula C11H8BrN3O. It is a pyrimidine derivative with a bromine atom attached to the 5th position and a phenyl group attached to the 2nd position. The compound contains a hydroxyl group at the 4th position. It is commonly used as a building block in organic synthesis and pharmaceutical research. Its potential applications include its use as an intermediate in the synthesis of biologically active compounds and as a starting material for the development of new drugs. Additionally, its unique structure and properties make it a candidate for further research in medicinal chemistry and drug development.

Upstream product

• 81560-03-4 2-methylsulfanyl-5-bromopyrimidin-4-one 
• 960-16-7 tributylphenylstannane 
• 33643-94-6 2-phenyl-4-hydroxypyrimidine 
• 15934-46-0 benzamidene hydrochloride 
• 33643-94-6 4-oxo-2-phenyl-3,4-dihydropyrimidine 

Downstream Products

• 26740-70-5 5-bromo-4-chloro-2-phenylpyrimidine 
• 1266479-98-4 4,5-dibromo-2-phenylpyrimidine 
• 1266476-75-8 5-bromo-N-(5-cyclopropyl-2H-pyrazol-3-yl)-2-phenyl-pyrimidin-4-amine 
• 27058-48-6 4-hydroxy-2-phenylpyrimidine-5-carbonitrile 

Relevant articles and documents

PYRIMIDINE COMPOUNDS AS TUBERCULOSIS INHIBITORS

The present invention relates to compounds II useful as inhibitors of treating tuberculosis. The invention also provides processes for preparing compounds of the invention.

SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE

The present invention relates to pyridines, pyrimidines and derivatives thereof, and pharmaceutically acceptable salts thereof. Also included is a method of treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myeloma, uveititis, acute or chronic myelogenous leukemia, pancreatic beta cell destruction, osteoarthritis, rheumatoid spondylitis, gouty arthritis, inflammatory bowel disease, adult respiratory distress syndrome (ARDS), psoriasis, Crohn's disease, allergic rhinitis, ulcerative colitis, anaphylaxis, contact dermatitis, asthma, muscle degeneration, cachexia, Reiter's syndrome, type I diabetes, type II diabetes, bone resorption diseases, graft vs. host reaction, Alzheimer's disease, stroke, myocardial infarction, ischemia reperfusion injury, atherosclerosis, brain trauma, multiple sclerosis, cerebral malaria, sepsis, septic shock, toxic shock syndrome, fever, myalgias due to HIV-1, HIV-2, HIV-3, cytomegalovirus (CMV), influenza, adenovirus, the herpes viruses or herpes zoster infection in a mammal comprising administering an effective amount a compound as described above.