26956-47-8

Basic information

• Product Name: 1-BENZYL-4-HYDROXY-5-AZAINDOLE
• Synonyms: 1-BENZYL-4-HYDROXY-5-AZAINDOLE;1-benzyl-1,5-dihydro-pyrrolo[3,2-c]pyridin-4-one;1-benzyl-1,5-dihydro-4H-pyrrolo[3,2-c]pyridin-4-one;1-Benzyl-1H-pyrrolo[3,2-c]pyridin-4(5H)-one;1-Benzyl-1H-pyrrolo[3,2-c]pyridine-4-ol;1-Benzyl-5H-pyrrolo[3,2-c]pyridin-4-one
• CAS NO: 26956-47-8
• Molecular Formula: C₁₄H₁₂N₂O
• Molecular Weight: 224.26208
• Mol File: 26956-47-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 473.926 °C at 760 mmHg
• Flash Point: 240.422 °C
• Appearance: /
• Density: 1.211 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.647
• PKA: 13.66±0.20(Predicted)
• CAS DataBase Reference: 1-BENZYL-4-HYDROXY-5-AZAINDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BENZYL-4-HYDROXY-5-AZAINDOLE(26956-47-8)
• EPA Substance Registry System: 1-BENZYL-4-HYDROXY-5-AZAINDOLE(26956-47-8)

Safety Data

• Hazardous Substances Data: 26956-47-8(Hazardous Substances Data)

Usage

General Description

1-Benzyl-4-hydroxy-5-azaindole is a chemical compound with a molecular formula C14H12N2O. It is a heterocyclic organic compound that contains a five-membered ring with nitrogen and oxygen atoms. 1-BENZYL-4-HYDROXY-5-AZAINDOLE has potential applications in pharmaceutical and medicinal chemistry due to its ability to interact with biological systems and potentially exhibit therapeutic properties. Its aromatic benzyl group and hydroxy substituent contribute to its chemical and biological properties, making it a subject of interest in drug discovery and development. Additionally, its unique structural features make it a valuable building block for the synthesis of more complex organic molecules.

InChI:InChI=1/C14H12N2O/c17-14-12-7-9-16(13(12)6-8-15-14)10-11-4-2-1-3-5-11/h1-9H,10H2,(H,15,17)

Upstream product

• 18159-24-5 1-benzyl-1H-pyrrole-2-carbaldehyde 
• 60290-03-1 (E)-3-(N-benzylpyrrol-2-yl)acrylic acid 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 327173-80-8 1-benzyl-4-bromo-1H-pyrrolo[3,2-c]pyridine 
• 35636-10-3 benzyl-1 chloro-4 pyrrolo<3,2-c>pyridine 
• 60290-21-3 4-chloro-1H-pyrrolo-[3,2-c]-pyridine 
• 271-34-1 5-azaindole 
• 54415-77-9 4,5-dihydro-4-oxo-1H-pyrrolo<3,2-c>pyridine 

Relevant articles and documents

One-pot synthesis of fused 2-pyridones from heteroarylacrylic acid via curtius rearrangement & microwave-assisted thermal electrocyclization

We investigated the one-pot synthesis of several fused 2-pyridone ring systems based on a Curtius rearrangement, followed by a microwave-assisted thermal electrocyclization of a 2-aza-6?-electron system including isocyanate. We synthesized seven heterocyclic compounds containing a fused 2-pyridone ring. In these results, the one-pot synthesis of fused 2-pyridone ring system 5 from (E)-acrylic acids 1 under microwave irradiation conditions was more effective than the conventional reaction conditions in terms of the yield and the reaction time.