270596-41-3

Basic information

• Product Name: (S)-3-AMINO-4-(4-CHLOROPHENYL)BUTANOIC ACID HYDROCHLORIDE
• Synonyms: RARECHEM AK PT 0071;(S)-3-AMINO-4-(4-CHLOROPHENYL)BUTANOIC ACID;(S)-3-AMINO-4-(4-CHLOROPHENYL)BUTANOIC ACID HYDROCHLORIDE;(S)-3-AMINO-4-(4-CHLORO-PHENYL)-BUTYRIC ACID-HCL;H-BETA-HOPHE(4-CL)-OH HCL;H-PHE(4-CL)-(C*CH2)OH HCL;L-BETA-HOMO(4-CHLOROPHENYL)ALANINE HYDROCHLORIDE;4-CHLORO-L-BETA-HOMOPHENYLALANINE HYDROCHLORIDE
• CAS NO: 270596-41-3
• Molecular Formula: C10H13Cl2NO2
• Molecular Weight: 250.12
• Product Categories: 3-Amino-4-phenylbutyric Acid Analogs;3-Amino-4-phenylbutanoic Acid Analogs;API intermediates;B-Amino
• Mol File: 270596-41-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 360.2°Cat760mmHg
• Flash Point: 171.6°C
• Appearance: /
• Density: 1.287g/cm³
• Vapor Pressure: 8.13E-06mmHg at 25°C
• Refractive Index: 1.577
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 3.76±0.10(Predicted)
• CAS DataBase Reference: (S)-3-AMINO-4-(4-CHLOROPHENYL)BUTANOIC ACID HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-AMINO-4-(4-CHLOROPHENYL)BUTANOIC ACID HYDROCHLORIDE(270596-41-3)
• EPA Substance Registry System: (S)-3-AMINO-4-(4-CHLOROPHENYL)BUTANOIC ACID HYDROCHLORIDE(270596-41-3)

Safety Data

• Hazardous Substances Data: 270596-41-3(Hazardous Substances Data)

Usage

General Description

The chemical (S)-3-AMINO-4-(4-CHLOROPHENYL)BUTANOIC ACID HYDROCHLORIDE is a hydrochloride salt of the compound (S)-3-amino-4-(4-chlorophenyl)butanoic acid. It is a derivative of the amino acid phenylalanine and is commonly used in research and pharmaceutical applications. (S)-3-AMINO-4-(4-CHLOROPHENYL)BUTANOIC ACID HYDROCHLORIDE has potential therapeutic applications due to its ability to modulate neurotransmitter receptors in the central nervous system. It may be used as a precursor in the synthesis of other chemical compounds and drugs, or as a tool in biochemical and pharmacological studies.

InChI:InChI=1/C10H12ClNO2/c11-8-3-1-7(2-4-8)5-9(12)6-10(13)14/h1-4,9H,5-6,12H2,(H,13,14)/t9-/m0/s1

Upstream product

• 1035695-08-9 5-[2-(4-chlorophenyl)-1-hydroxyethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 1878-66-6 4-chlorophenylacetic Acid 

Downstream Products

• 270596-43-5 N-(9-fluorenylmethyloxycarbonyl)-L-β-homo-p-chlorophenylalanine 

Relevant articles and documents

Chiral synthesis method for chiral beta-amino acid and synthesis method for medicinal intermediate

The invention relates to a chiral synthesis method for chiral beta-amino acid. The chiral synthesis method comprises the following steps: reacting a compound shown in formula (II) with an acylation reagent to prepare anhydride intermediate reaction liquid under the action of alkali; adding Meldrum's acid into the anhydride intermediate reaction liquid, and performing reaction to generate a compound shown in formula (III); reacting the compound shown in formula (III) with a compound shown in formula (IV) to generate a compound shown in formula (V); reducing the compound shown in formula (V) to generate a compound shown in formula (VI); performing acidic hydrolysis on the compound shown in formula (VI) to generate a compound shown in formula (I), i.e., the chiral beta-amino acid. The chiral synthesis method has the advantages of convenience for synthesis, low cost and simple process, and compared with a disclosed preparation method, is more suitable for industrial production.