27143-81-3

Basic information

• Product Name: (2,2-dimethylpropylidyne)azane oxide
• Synonyms: Propanenitrile,2,2-dimethyl-, N-oxide
• CAS NO: 27143-81-3
• Molecular Formula: C₅H₉NO
• Molecular Weight: 99.1311
• Mol File: 27143-81-3.mol
• Article Data: 6

Chemical Properties

• Density: 0.84g/cm³
• Refractive Index: 1.416
• CAS DataBase Reference: (2,2-dimethylpropylidyne)azane oxide(CAS DataBase Reference)
• NIST Chemistry Reference: (2,2-dimethylpropylidyne)azane oxide(27143-81-3)
• EPA Substance Registry System: (2,2-dimethylpropylidyne)azane oxide(27143-81-3)

Safety Data

• Hazardous Substances Data: 27143-81-3(Hazardous Substances Data)

Upstream product

• 630-19-3 pivalaldehyde 
• 637-91-2 2,2-dimethylpropionaldehyde oxime 
• 74903-82-5 (1Z)-N-hydroxy-2,2-dimethylpropanimidoyl chloride 
• 3273-26-5 1-chloro-2,2-dimethyl-propan-1-one oxime 

Downstream Products

• 111271-10-4 3-tert-butyl-5,5-dimethoxy-4-phenyl-4,5-dihydro-isoxazole 
• 42052-52-8 1-hydroxy-4,4-dimethyl-1-phenylpentan-3-one 
• 91157-60-7 cis-2-(2,2-Dimethyl-1-oxopropyl)cyclohexanol 
• 59671-45-3 3,3-dimethyl-1-(1-hydroxycyclohexyl)-2-butanone 
• 100717-95-1 3-tert-butyl-5-methoxy-4-phenyl-isoxazole 
• 127311-22-2 6-(N-methyl)benzamido-3-tert-butyl-3aα,5,6β,6aα-tetrahydro-4H-cyclopentisoxazole 
• 756896-01-2 (3aR,6aR)-3-tert-Butyl-5-((S)-1-phenyl-ethyl)-3a,5,6,6a-tetrahydro-1-oxa-4-thia-2,5-diaza-pentalene 4,4-dioxide 
• 756895-88-2 (3aS,6aS)-3-tert-Butyl-5-((S)-1-phenyl-ethyl)-3a,5,6,6a-tetrahydro-1-oxa-4-thia-2,5-diaza-pentalene 4,4-dioxide 
• 701209-15-6 (4S,5S)-5-[(1-benzyl-5,5-dimethyl-3-oxo-2-pyrazolidinyl)carbonyl]-4-methyl-3-tert-butyl-4,5-dihydroisoxazole 
• 94981-77-8 3,4-bis(1,1-dimethylethyl)furoxan 

Relevant articles and documents

One-pot copper(I)-catalyzed synthesis of 3,5-disubstituted isoxazoles

3,5-Disubstituted isoxazoles are obtained in good yields by a convenient one-pot, three-step procedure utilizing a regioselective copper(I)-catalyzed cycloaddition reaction between in situ generated nitrile oxides and terminal acetylenes. Most functional

Diastereoselective [3+2] cycloadditions of a camphor-derived chiral N- acryloylhydrazide with nitrile oxides: The preparation of optically pure δ2-isoxazolines

Reaction of a novel chiral N-acryloylhydrazide with various nitrile oxides proceeded smoothly to afford the cycloadduct with high diastereoselectivity (99:1). The auxiliary can be easily removed from the cycloadducts under mild conditions. (C) 2000 Elsevier Science Ltd.

Cycloadditions, 18: 5-Aminoisoxazoles by Cycloaddition of Nitrile Oxides to Ynamines

Ten differently substituted ynamines 1a-j react with five nitrile oxides 3a-e to give the 5-aminoisoxazoles 4a-z.The stannyl-substituted ynamine 1k furnishes the same compounds (e.g. 4a-d) by reaction with the hydroximoyl chlorides 2a-d.Two representatives of 4 - b and p - can be transformed into the corresponding 1-azirine-3-carboxamides 6a and b.