42052-52-8

Basic information

• Product Name: 3-Pentanone, 1-hydroxy-4,4-dimethyl-1-phenyl-
• CAS NO: 42052-52-8
• Molecular Formula: C13H18O2
• Molecular Weight: 206.285
• Mol File: 42052-52-8.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 3-Pentanone, 1-hydroxy-4,4-dimethyl-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pentanone, 1-hydroxy-4,4-dimethyl-1-phenyl-(42052-52-8)
• EPA Substance Registry System: 3-Pentanone, 1-hydroxy-4,4-dimethyl-1-phenyl-(42052-52-8)

Safety Data

• Hazardous Substances Data: 42052-52-8(Hazardous Substances Data)

Upstream product

• 60143-76-2 Benzoyl-pivaloyl-methan (Enolform); 1-Phenyl-4,4-dimethyl-1-hydroxy-3-oxo-penten-⁽¹⁾ 
• 84896-29-7 4,4-dimethyl-1-phenyl-1-((trimethylsilyl)oxy)pentan-3-one 
• 75-97-8 3,3-dimethyl-butan-2-one 
• 538-44-3 4,4-dimethyl-1-phenyl-1-penten-3-one 
• 13547-70-1 1-chloro-3,3-dimethyl-butan-2-one 
• 100-52-7 benzaldehyde 
• 27143-81-3 tert-butyl nitrile oxide 
• 74903-82-5 (1Z)-N-hydroxy-2,2-dimethylpropanimidoyl chloride 
• 17510-46-2 3,3-dimethyl-2-(trimethylsilyl)oxy-1-butene 
• 180511-99-3 allyl 4,4-dimethyl-3-oxopentanoate 
• 13988-67-5 benzoylpivaloylmethane 
• 99714-13-3 iodo-1 dimethyl-3,3 butanone-2 
• 202744-38-5 trichloro<<1-(1,1-dimethylethyl)ethenyl>oxy>silane 
• 5469-26-1 1-Bromopinacolon 

Downstream Products

• 538-44-3 (E)-benzylidenepinacolone 
• 67565-05-3 1-imidazol-1-yl-4,4-dimethyl-1-phenyl-pentan-3-one 
• 5195-24-4 4,4-dimethyl-1-phenylpentan-3-one 
• 107369-60-8 2,2-Dimethyl-5-phenyl-pentandiol-(3,5) 
• 18335-34-7 syn-4,4-dimethyl-1-phenylpentane-1,3-diol 
• 132157-40-5 (1R*,3R*)-4,4-Dimethyl-1-phenyl-1,3-pentanediol 
• 5397-27-3 tert-butyl 3-hydroxy-3-phenylpropionate 
• 538-44-3 4,4-dimethyl-1-phenyl-1-penten-3-one 
• 95546-35-3 1-bromo-4,4-dimethyl-1-phenyl-pentan-3-one 
• 95546-07-9 1-chloro-4,4-dimethyl-1-phenyl-pentan-3-one 

Relevant articles and documents

Experimental evidence for chair-like transition states in aldol reactions of methyl ketone lithium enolates: Stereoselective synthesis and utilization of a deuterium-labeled enolate as a probe of reaction stereochemistry

Aldol reactions of methyl ketone lithium enolates proceed via chairlike Zimmerman-Traxler transition states with 7:1 to 50:1 preference over alternative, boatlike transition structures, as determined by studies involving the configurationally stable deute

One-pot enol silane formation-Mukaiyama aldol reactions: Crossed aldehyde-aldehyde coupling, thioester substrates, and reactions in ester solvents

Trimethylsilyl trifluoromethanesulfonate (TMSOTf) and a trialkylamine base promote both in situ enol silane/silyl ketene acetal formation and Mukaiyama aldol addition reactions between a variety of reaction partners in a single reaction flask. Isolation of the required enol silane or silyl ketene acetal is not necessary. For example, crossed aldol reactions between α-disubstituted aldehydes and non-enolizable aldehydes yield β-hydroxy aldehydes in good yield. In a related reaction, the common laboratory solvent ethyl acetate functions as both an enolate precursor and a green reaction solvent. When thioesters are employed as enolate precursors, high yields for additions to non-enolizable aldehydes are routinely observed.

Methods of preparing organic boron compound and beta-carbonyl compound by catalyzing copper ion loaded chitosan microspheres

The invention relates to methods of preparing an organic boron compound and a beta-carbonyl compound by catalyzing copper ion loaded chitosan microspheres. The preparation method of the organic boroncompound mainly comprises the following steps of A, addi

Organotin perfluorooctanesulfonates as air-stable Lewis acid catalysts: Synthesis, characterization, and catalysis

The reactions of 1,3-dichloro-1,1,3,3-tetrabutyldistannoxane and di-alkyltin dihalides with silver perfluoro-octanesulfonate provided the corresponding sulfonates as hydrates. The number of water molecules (n) of hydration was dependent on the conditions. The distannoxane derivative was identified as n from 0.5 to 6, while in the hydrated mononuclear species and DMSO complexes n varied widely from 4 to 13. 119Sn NMR spectroscopy and conductivity measurements indicated the ionic dissociation of these compounds in solution. These compounds exhibited unusually high solubility in polar organic solvents. The ionic dissociation together with facile hydration probably causes the unusual solubility. The Lewis acidity of these compounds was found to be high among organotin derivatives on the basis of ESR spectra of Superoxide/ metal-ion complexes. In contrast to well-known organotin Inflates, these compounds suffered no hydrolysis upon storage in open air. The high catalytic activity of the distannoxane 1 was exemplified for various carboncarbon bond-forming reactions, such as Mukaiyama-aldol as well as -Michael reactions and allylation of aldehydes.