27159-32-6

Basic information

• Product Name: 1-(Benzylamino)propan-2-ol
• Synonyms: 1-(Benzylamino)propan-2-ol;1-Benzylamino-2-propanol;N-Benzyl-N-(2-hydroxypropyl)amine;2-Propanol, 1-((phenylmethyl)amino)-;Ai3-52530;Einecs 248-274-2;1-[(phenylmethyl)amino]-2-Propanol
• CAS NO: 27159-32-6
• Molecular Formula: C₁₀H₁₅NO
• Molecular Weight: 165.23
• EINECS: 248-274-2
• Mol File: 27159-32-6.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 292.2 °C at 760 mmHg
• Flash Point: 119.9 °C
• Appearance: /
• Density: 1.02 g/cm³
• Vapor Pressure: 0.000848mmHg at 25°C
• Refractive Index: 1.531
• Storage Temp.: 2-8°C
• PKA: 14.66±0.20(Predicted)
• CAS DataBase Reference: 1-(Benzylamino)propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Benzylamino)propan-2-ol(27159-32-6)
• EPA Substance Registry System: 1-(Benzylamino)propan-2-ol(27159-32-6)

Safety Data

• Hazardous Substances Data: 27159-32-6(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 30, p. 4255, 1989 DOI: 10.1016/S0040-4039(01)80704-8

InChI:InChI=1/C10H15NO/c1-9(12)7-11-8-10-5-3-2-4-6-10/h2-6,9,11-12H,7-8H2,1H3

Upstream product

• 100-52-7 benzaldehyde 
• 78-96-6 3-amino-2-propanol 
• 100-46-9 benzylamine 
• 75-56-9 methyloxirane 
• 125582-79-8 C₁₉H₃₅NPb 
• 100-44-7 benzyl chloride 
• 199595-94-3 1-Benzyl-1,4,5,6-tetrahydro-[1,2,3]triazine 
• 100-39-0 benzyl bromide 
• 5456-01-9 N-benzylidene-2-hydroxypropane-1-amine 
• 57-55-6 propylene glycol 

Downstream Products

• 100522-36-9 1-(benzyl-propyl-amino)-propan-2-ol 
• 1135490-84-4 N-benzyl-3-chloro-N-(2-hydroxypropyl)-1,2-dihydrocyclobutabenzene-1-carboxamide 
• 1135490-97-9 N-benzyl-4-bromo-3-chloro-N-(2-hydroxypropyl)-1,2-dihydrocyclobutabenzene-1-carboxamide 
• 1420476-87-4 2-benzyl-7-bromo-4-methyl-3,4-dihydro-1H-pyrido[1,2-a]pyrazine-1,6(2H)-dione 
• 956434-21-2 N-benzyl-2-{[tert-butyl(dimethyl)silyl]oxy}propan-1-amine 
• 1423166-07-7 1-(2-benzyl-1,1-dioxo-isothiazolidin-3-yl)-ethanone 
• 1423165-99-4 2-benzyl-4-methyl-5-methylene-1,1-dioxo-isothiazolidin-4-ol 
• 1423165-83-6 7-methyl-5-benzyl-[1,4,5]-oxathiazepane-4,4-dioxide 
• 1423165-91-6 C₁₂H₁₅NO₃S 
• 1423165-75-6 C₁₂H₁₇NO₃S 
• 1423165-67-6 C₁₈H₃₁NO₃SSi 
• 1427715-66-9 C₁₈H₂₂ClNO₂ 
• 118460-18-7 2-[Benzyl-(2-hydroxy-propyl)-amino]-N-(1-phenyl-ethyl)-acetamide 
• 61636-35-9 4-benzyl-6-methyl-morpholin-3-one 

Relevant articles and documents

Microwave-Assisted CuCl-Catalyzed Three-Component Reactions of Alkynes, Aldehydes, and Amino Alcohols

A microwave (MW)-assisted three-component coupling of amino alcohols, aldehydes, and alkynes is developed under catalysis by CuCl. Compared with thermal conditions, MW irradiation greatly increases the reaction efficiency. The reactions of various primary N -alkyl/arylamino alcohols, aliphatic/aromatic aldehydes, and alkynes are systematically investigated, affording the desired products in moderate to good yields. Notably, acetylene is also an effective reactant under the current MW-assisted conditions.

Ruthenium-Catalyzed Amination of Secondary Alcohols Using Borrowing Hydrogen Methodology

A new ruthenium complex catalyzes the amination of primary and secondary alcohols and the regioselective mono- and sequential diamination of diols via the borrowing hydrogen pathway. Several variations on new intra- and intermolecular cyclizations of aminoalcohols, diols, and diamines lead to heterocyclic ring systems.

Regioselective ring opening in epoxides under the action of amines in water medium

Amino(bis-amino)derivatives of 2-propanol were synthesized by ring opening in epoxides under the action of amines in water medium using environmentally safe methods. The structure of the compounds obtained was established by elemental analysis and the IR, 1H and 13C NMR spectroscopy. It was found that these substances are effective bactericides. They suppress the growth of the sulfate-reducing bacteria and exhibit high anticorrosive properties.