27301-45-7

Basic information

• Product Name: 5-(4-chlorophenyl)-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole
• CAS NO: 27301-45-7
• Molecular Formula: C₂₂H₁₇ClN₂O
• Molecular Weight: 360.8362
• Mol File: 27301-45-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 528.5°C at 760 mmHg
• Flash Point: 273.4°C
• Density: 1.19g/cm³
• Vapor Pressure: 9.98E-11mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: 5-(4-chlorophenyl)-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-chlorophenyl)-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole(27301-45-7)
• EPA Substance Registry System: 5-(4-chlorophenyl)-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole(27301-45-7)

Safety Data

• Hazardous Substances Data: 27301-45-7(Hazardous Substances Data)

Usage

Chemical Class

Pyrazole derivatives
A 4-chlorophenyl group at the 5-position
A 4-methoxyphenyl group at the 3-position
A phenyl group at the 1-position

Biological Activities

Anti-inflammatory: Potential to reduce inflammation in biological systems.
Analgesic: Potential to alleviate pain sensations.

Potential Applications

Lead Compound: Could be used as a starting point for developing new drugs.
Disease Treatment: Potential for treating various diseases.

Utility in Research and Development

Chemical Research: Useful in studying chemical reactions and properties.
Pharmaceutical Development: Valuable in the creation of new pharmaceutical products.

Upstream product

• 1340547-59-2 C₁₈H₁₇ClO₂S 
• 100-63-0 phenylhydrazine 
• 6552-68-7 4'-methoxy-4-chlorochalcone 
• 1380819-96-4 C₂₂H₁₉ClN₂O 
• 75745-49-2 5-(4-chlorophenyl)-3-(4-methoxyphenyl)-1-phenyl-4,5-dihydro-1H-pyrazole 

Relevant articles and documents

Regioselective synthesis of 1,3,5-trisubstituted pyrazoles

A new and a simple approach toward synthesis of 1,3,5-trisubstituted pyrazoles from chalcone arylhydrazones via oxidative cyclization has been achieved. 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone was successfully used as an oxidizing agent to give excellen

4-(p-Chloro)phenyl-1,2,4-triazole-3,5-dione as a novel and reusable reagent for the oxidation of 1,3,5-trisubstituted pyrazolines under mild conditions

4-(p-Chloro)phenyl-1,3,4-triazole-3,5-dione is used as an effective oxidizing agent for the oxidation of 1,3,5-trisubstituted pyrazolines to their corresponding pyrazoles under mild conditions with moderate to good yields at room temperature.

Tricholoroisocyanuric acid as a useful reagent in microwave-assisted aromatization of 1,3,5-trisubstituted 2-pyrazolines

An efficient aromatization of 1,3,5-trisubstituted 2-pyrazolines to their corresponding pyrazoles has been performed by tricholoroisocyanuric acid [TCCA] under microwave irradiation in excellent yields. It has been observed that the reactions occur more r