75745-49-2Relevant articles and documents
An eco-friendly synthesis of 2-pyrazoline derivatives catalysed by CeCl 3· 7 H 2O
Bhat, Prabhat,Shridhar, Gomathi,Ladage, Savita,Ravishankar, Lakshmy
, p. 1441 - 1448 (2017/09/25)
Abstract: 1,3,5-triaryl-2-pyrazoline derivatives were synthesised by a condensation reaction between chalcones and phenyl hydrazine using cerium chloride heptahydrate as a catalyst. All these reactions were carried out in ethyl lactate (70%) as a green solvent. Easy and efficient work up, recyclability of solvent and catalyst are the key merits of this protocol. Graphical Abstract:: SYNOPSIS A facile protocol for the synthesis of 1,3,5-triaryl-2-pyrazolines is described. The solvent ethyl lactate, obtained from renewable sources, is biodegradable. The catalyst CeCl 3· 7 H 2O is a water-tolerant Lewis acid with low toxicity. Easy and clean work up, recyclable solvent and catalyst are merits of the protocol. The reaction works well for all systems giving good yields of the desired products.[Figure not available: see fulltext.].
Thiocyanation on n-benzene rings of 1,3,5-trisubstituted pyrazolines with oxone
Wu, Guaili,Liang, Ruirui,Chen, Yongjiang,Wu, Longmin
experimental part, p. 129 - 134 (2010/03/24)
An efficient aromatic thiocyanation of 1,3,5-trisubstituted pyrazolines occurred regioselectively at the para position of N-benzene rings using ammonium thiocyanate as a thiocyanation reagent and oxone as an oxidant.
Silica-supported synthesis of some 1,3,5-trisubstituted 2-pyrazolines under solvent-free and microwave irradiation conditions
Azarifar, Davood,Maleki, Behrooz
, p. 157 - 159 (2007/10/03)
A simple method for the synthesis of 2-pyrazolines is described which occurs on silica surface under solvent-free conditions within 110-180 sec using microwave irradiation. The results obtained indicate that the use of silica gel as a support in pyrazolin
