2761-08-2

Basic information

• Product Name: ACRYLICACID,3-HYDROXYPROPYLESTER
• Synonyms: ACRYLICACID,3-HYDROXYPROPYLESTER;1-HYDROXY-3-PROPYLACRYLATE;Propanediol monoacrylate;1,3-Propanediol 1-acrylate
• CAS NO: 2761-08-2
• Molecular Formula: C₆H₁₀O₃
• Molecular Weight: 130.14
• Mol File: 2761-08-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 224.5±23.0 °C(Predicted)
• Appearance: /
• Density: 1.052±0.06 g/cm3(Predicted)
• PKA: 14.67±0.10(Predicted)
• CAS DataBase Reference: ACRYLICACID,3-HYDROXYPROPYLESTER(CAS DataBase Reference)
• NIST Chemistry Reference: ACRYLICACID,3-HYDROXYPROPYLESTER(2761-08-2)
• EPA Substance Registry System: ACRYLICACID,3-HYDROXYPROPYLESTER(2761-08-2)

Safety Data

• Hazardous Substances Data: 2761-08-2(Hazardous Substances Data)

Upstream product

• 91668-21-2 3-hydroxypropyl 3-hydroxypropanoate 
• 79-10-7 acrylic acid 
• 75-56-9 methyloxirane 
• 292638-85-8 acrylic acid methyl ester 
• 504-63-2 trimethyleneglycol 

Downstream Products

• 130977-34-3 2-(Hydroxy-p-tolyl-methyl)-acrylic acid 3-hydroxy-propyl ester 
• 130977-33-2 2-(Hydroxy-phenyl-methyl)-acrylic acid 3-hydroxy-propyl ester 

Relevant articles and documents

Method for synthesizing alkyl (meth) acrylate

The invention discloses a synthesis method of alkyl (meth) acrylate, and belongs to the field of organic chemical synthesis. The synthesis method of the present invention employs a heterogeneous solid acid catalyst. The polymerization inhibitor and (meth) acrylic acid were put into the reaction kettle and heated to 50 - 90 °C, and an epoxide was introduced into the reaction kettle for reaction. The reaction solution is filtered to remove the homogeneous solid acid catalyst and the rectification to obtain the target product. The synthesis method not only can improve the selectivity of a target product (methyl) acrylic acid alkyl ester, but also can effectively inhibit the generation of high-boiling-point double esters of by-products generated by the addition of bis (methyl) acrylic acid.

Hydroxy functional acrylate and methacrylate monomers prepared via lipase-catalyzed transacylation reactions

Candida antarctica lipase B (CAL-B, Novozyme 435) catalyzes the transacylation of methyl acrylate and methyl methacrylate with diols and triols in 2-methyl-2-butanol at 50 °C. Under the experimental conditions, up to 70 mol% of the acyl donor methyl acrylate was converted. Methyl methacrylate is the less efficient acyl donor (up to 60 mol%) due to the higher sterical hindrance in the enzymatic transacylation. Under the reaction conditions high yields of the mono-acylated products are obtained, which contain minor amounts of bis(meth)acrylates. In addition it was observed that Novozyme 435 catalyzes regioselectively the acylation of the primary hydroxyl groups. In comparison with the chemical catalyzed route no selectivity was observed for unsubstituted diols. For substituted diols more mono-acylated product was formed in the lipase-catalyzed reaction than in the chemical catalyzed reaction.

PURIFICATION OF 1,3-PROPANEDIOL BY DISTILLATION

The present invention is a process for purification of 1,3-propanediol (PDO) by an inverted distillation sequence which comprises: (a) optionally removing water or other solvents from the crude 1,3-propanediol mixture; (b) distilling the crude 1,3-propanediol mixture under conditions which maximize the separation of components of the mixture which are heavier than 1,3-propanediol from the 1,3-propanediol and the components which are lighter than 1,3-propanediol; (c) drawing off a stream which contains at least most of the 1,3-propanediol and at least some of the components of the mixture which are lighter than 1,3-propanediol; and (d) distilling the stream of (c) to separate the 1,3-propanediol from components in the stream which are lighter than 1,3-propanediol and any residual components which are heavier than 1,3-propanediol.