27882-76-4

Basic information

• Product Name: ChromiumPolynicotinate
• Synonyms: CHROMIUMPICOLINATEMONOHYDRATE
• CAS NO: 27882-76-4
• Molecular Formula: C₁₈H₁₂CrN₃O₆*H₂O
• Molecular Weight: 0
• Mol File: 27882-76-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 292.5°C at 760 mmHg
• Flash Point: 130.7°C
• Appearance: /
• Vapor Pressure: 0.000836mmHg at 25°C
• CAS DataBase Reference: ChromiumPolynicotinate(CAS DataBase Reference)
• NIST Chemistry Reference: ChromiumPolynicotinate(27882-76-4)
• EPA Substance Registry System: ChromiumPolynicotinate(27882-76-4)

Safety Data

• Hazardous Substances Data: 27882-76-4(Hazardous Substances Data)

Usage

General Description

Chromium polynicotinate is a chemical compound that is formed by binding chromium with niacin, also known as vitamin B3. It is often used as a dietary supplement to support healthy glucose and lipid metabolism. Chromium polynicotinate is believed to be more bioavailable and safer than other forms of chromium supplements, such as chromium picolinate. Some research suggests that it may have potential benefits for managing blood sugar levels, supporting cardiovascular health, and promoting weight management. However, further studies are needed to fully understand the effectiveness and safety of chromium polynicotinate as a supplement. It is important to consult with a healthcare professional before using this or any other dietary supplement.

InChI:InChI=1/C6H5NO2.Cr.H2O/c8-6(9)5-3-1-2-4-7-5;;/h1-4H,(H,8,9);;1H2/p-1

Upstream product

• 98-98-6 2-Picolinic acid 
• 636-80-6 2-picolinic acid hydrochloride 

Relevant articles and documents

Chromium(III) Compounds with Some Organic Ligands

Abstract: The equilibrium acquisition times in chromium(III)?organic ligand systems were determined under various conditions. Chromium(III) compounds with picolinic acid Cr(C6H4NO2)3 ? H2O, nicotinic acid CrOH(C6H4NO2)2 ? 2H2O, and citric acid CrC6H5O7 ? 3H2O were isolated; their gravimetric and thermogravimetric analyses carried out; and IR spectra measured. The major chromium(III) complex species with the above-listed acid anions in solutions were found to have a (1 : 1) stoichiometry using isomolar series; their stability constants were determined by potentiometric measurements. The electronic absorption spectra of the systems were analyzed. The photometric determination of chromium picolinate in solutions was developed, the solubility constant KS was determined (log KS = –21.52 ± 0.29), quantum-chemical calculations carried out for a gaseous molecule, and energy and geometric parameters calculated.

Estimation of the pKa for various Br?nsted acids in polar aprotic media using electrochemical measurements of chromium (III) with picolinic acid

The electrochemical reduction of Crpic and the effect of various proton-donors in DMF were investigated in this work. Measurements showed important electrochemical changes in the presence of proton-donors such as ascorbic acid, benzoic acid and acetic acid. Dissociation constants and acid strength are estimated using the Nernstian behavior of the chromium (III) complex and the proportional relation between ΔEp vs pKa are assistance to estimate the dissociation constants and the acid strength.

Kinetics of Substitution of Aquo Ligands from Hexaaquochromium(III) Ion by Picolinic Acid in Water-Ethanol Medium

The kinetics of substitution of aquo ligands from hexaaquochromium(III) ion by picolinic acid in water-ethanol medium (30percent, v/v) has been studied spectrophotometrically.The following rate law has been established in the pH range 3.72 to 4.98, where KE is the ion pair equilibrium constant and k, the rate constant for conversion of outer sphere complex to inner sphere complex.The reaction rate is found to be pH dependent in the pH range 3.72 to 4.98.Activation parameters have been calculated and compared with water exchange reaction and other substitution reactions of hexaaquochromium(III) ion.A mechanism involving outer sphere association between the two reactant species, followed by transformation of this outer sphere complex into the product by an associative path has been suggested.