284024-88-0

Basic information

• Product Name: ethyl (2S,4R)-N-Boc-4-(3-phenylpropyl)pyroglutamate
• Synonyms: ethyl (2S,4R)-N-Boc-4-(3-phenylpropyl)pyroglutamate
• CAS NO: 284024-88-0
• Molecular Weight: 375.465
• Mol File: 284024-88-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl (2S,4R)-N-Boc-4-(3-phenylpropyl)pyroglutamate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (2S,4R)-N-Boc-4-(3-phenylpropyl)pyroglutamate(284024-88-0)
• EPA Substance Registry System: ethyl (2S,4R)-N-Boc-4-(3-phenylpropyl)pyroglutamate(284024-88-0)

Safety Data

• Hazardous Substances Data: 284024-88-0(Hazardous Substances Data)

Upstream product

• 4392-24-9 Cinnamyl bromide 
• 144978-35-8 (S)-ethyl N-tert-butoxycarbonylpyroglutamate 
• 153080-83-2 ethyl (2S,4R,E)-N-BOC-4-cinnamylpyroglutamate 

Downstream Products

• 359028-91-4 (6S,8R)-1-Chloro-4-oxo-8-(3-phenyl-propyl)-3-(3-trifluoromethyl-benzylamino)-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid ethyl ester 
• 359028-92-5 (6S,8R)-1-Chloro-4-oxo-8-(3-phenyl-propyl)-3-(3-trifluoromethyl-benzylamino)-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid 
• 359028-90-3 (6S,8R)-1,3-Dichloro-4-oxo-8-(3-phenyl-propyl)-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid ethyl ester 
• 359028-87-8 (2S,4R)-5-Cyano-4-(3-phenyl-propyl)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester 
• 359028-88-9 (2S,4R)-5-Cyano-4-(3-phenyl-propyl)-pyrrolidine-2-carboxylic acid ethyl ester 
• 359028-86-7 (2S,4R)-5-Methoxy-4-(3-phenyl-propyl)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester 
• 129413-91-8 (2S,4R)-2-tert-Butoxycarbonylamino-4-(3-phenyl-propyl)-pentanedioic acid 
• 129413-93-0 (2S,4R)-2-amino-4-(3-phenylpropyl)pentanedioic acid 

Relevant articles and documents

Design and synthesis of potent, non-peptide inhibitors of HCV NS3 protease

Starting from a hexapeptide boronic acid lead, 3-amino bicyclic pyrazinones as novel β-sheet dipeptide mimetics have been designed and synthesized. Side-chain manipulation of this scaffold generated a series of potent, nonpeptidic inhibitors of HCV NS3 protease.

(2S,3S)-2-Amino-3-(2,2-diphenylethyl)pentanedioic acid selective group 2 metabotropic glutamate receptor antagonist

(2S,4S)-2-Amino-4-(4,4-diphenylbut-1-yl)-pentane-1,5-dioic acid 1m, is a novel metabotropic glutamate receptor (mGluR) antagonist with insignificant ionotropic affinity. It is a selective antagonist of negatively-coupled cAMP-linked mGluRs with no effect