28458-93-7Relevant articles and documents
Catalytic Direct Cyanomethylenation of C(sp3)–H Bonds via a One-Step Double C–C Bond Formation
Bhadra, Sukalyan,Kumar, Jogendra,Singh, Anupam Kumar
supporting information, p. 1512 - 1517 (2022/01/27)
An elegant and catalytic procedure for the one-step cyanomethylenation of C(sp3)–H bonds adjacent to benzazoles and ketones is described herein using DMF as a C-1 unit and TMSCN as the cyanide source. The copper-mediated reaction between DMF an
Synthesis method of 2-aryl formyl benzoxazole compound
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Paragraph 0046-0052, (2021/06/21)
The invention discloses a synthesis method of a 2-aryl formyl benzoxazole compound, which comprises the following steps: in an oxygen-containing atmosphere and an ultrasonic environment, carrying out intramolecular cyclization-oxidation cascade reaction on N-(2-hydroxyphenyl)-2-aryl acetamide under the synergistic catalysis action of an acidic eutectic solvent and a cuprous salt, thereby obtaining the 2-aryl formyl benzoxazole compound. The method is mild in reaction condition, simple in step, green, energy-saving, high in reaction selectivity and product yield and excellent in substrate functional group compatibility, the acidic eutectic solvent/cuprous salt catalytic system can be recycled for multiple times, and the production cost is greatly reduced.
Electrochemical Oxidative Functionalization of Arylalkynes: Access to α,α-Dibromo Aryl Ketones
Wang, Dan,Wan, Zhaohua,Zhang, Heng,Lei, Aiwen
, p. 1022 - 1027 (2020/12/31)
A general and effective protocol to synthesize α,α-dibromo aryl ketones has been developed via an electrochemical oxidative method. The reaction proceeds smoothly at room temperature in an undivided cell without the addition of external oxidants. In the reaction process, LiBr acts as both bromine source and supporting electrolyte. This electrooxidation strategy has good substrate applicability and functional group compatibility. Moreover, the reaction could be scaled up efficiently in a continuous flow cell. The target product could undergo further functionalization for the synthesis of some useful heterocyclic compounds. (Figure presented.).
