76929-77-6

Basic information

• Product Name: 1,3-benzoxazol-2-yl(diphenyl)methanol
• CAS NO: 76929-77-6
• Molecular Formula: C₂₀H₁₅NO₂
• Molecular Weight: 301.3386
• Mol File: 76929-77-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 491.1°C at 760 mmHg
• Flash Point: 250.8°C
• Density: 1.253g/cm³
• Vapor Pressure: 1.85E-10mmHg at 25°C
• Refractive Index: 1.665
• CAS DataBase Reference: 1,3-benzoxazol-2-yl(diphenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-benzoxazol-2-yl(diphenyl)methanol(76929-77-6)
• EPA Substance Registry System: 1,3-benzoxazol-2-yl(diphenyl)methanol(76929-77-6)

Safety Data

• Hazardous Substances Data: 76929-77-6(Hazardous Substances Data)

Usage

Appearance

White solid

Usage

Reactant in the synthesis of various pharmaceuticals and organic compounds

Biological activities

Antiviral, antibacterial, and antifungal properties

Potential applications

Development of new materials and as a fluorescent dye

Industries

Pharmaceutical and materials science industries

Upstream product

• 536-74-3 phenylacetylene 
• 74966-68-0 2,2-diiodo-1-phenylethan-1-one 
• 2648-61-5 2,2-dichloroacetophenone 
• 95-55-6 2-amino-phenol 
• 13665-04-8 2,2-dibromoacetophenone 
• 28458-93-7 benzo[d]oxazol-2-yl(phenyl)methanone 
• 100-58-3 phenylmagnesium bromide 
• 273-53-0 benzoxazole 
• 119-61-9 benzophenone 
• 408538-63-6 benzo[d]oxazole-2-carbonyl chloride 

Downstream Products

• 73713-90-3 α-(2-benzoxazolyl)diphenylmethane 

Relevant articles and documents

Synthesis of 2-Keto(hetero)aryl Benzox(thio)azoles through Base Promoted Cyclization of 2-Amino(thio)phenols with α,α-Dihaloketones

An interesting base-promoted protocol for the synthesis of 2-keto(hetero)aryl benzox(thi)azoles has been developed. Starting from commercially available 2-amino(thio)phenols and α,α-dihaloketones, moderate to good yields of the corresponding heterocycles can be achieved. Notably, only EtNH2 was required as the promoter here, and the reaction can be easily performed on a large scale.

Reduction of 1,3-azole and 1,3-benzazole carbinols with sodium borohydride-trifluoroacetic acid

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