28610-34-6

Basic information

• Product Name: 6,6-dimethyldihydropyran (2,3:7,8)-5,4'-dihydroxyflavonol
• Synonyms: 6,6-dimethyldihydropyran (2,3:7,8)-5,4'-dihydroxyflavonol
• CAS NO: 28610-34-6
• Molecular Weight: 354.359
• Mol File: 28610-34-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 6,6-dimethyldihydropyran (2,3:7,8)-5,4'-dihydroxyflavonol(CAS DataBase Reference)
• NIST Chemistry Reference: 6,6-dimethyldihydropyran (2,3:7,8)-5,4'-dihydroxyflavonol(28610-34-6)
• EPA Substance Registry System: 6,6-dimethyldihydropyran (2,3:7,8)-5,4'-dihydroxyflavonol(28610-34-6)

Safety Data

• Hazardous Substances Data: 28610-34-6(Hazardous Substances Data)

Upstream product

• 641-94-1 amurensin 
• 28610-31-3 8-prenylkaempferol 
• 83171-42-0 4,6-dimethoxy-2-(4'-methoxybenzoyloxy)acetophenone 
• 90-24-4 2-hydroxy-4,6-dimethoxyacetophenone 
• 143724-70-3 5-O-prenyl-3,7,4'-tris-O-methoxymethylkaempferol 
• 1329801-99-1 3,5-hydroxy-4',7-dimethoxymethylflavone 
• 118075-12-0 2'-hydroxy-4,4',6'-trimethoxymethoxylchalcone 
• 6515-21-5 4-methoxymethoxy-benzaldehyde 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 870-63-3 prenyl bromide 
• 143724-76-9 5-hydroxy-8-prenyl-3,4',7-tris-O-methoxymethylkaempferol 
• 143724-66-7 3,4',7-tris-O-methoxymethylkaempferol 
• 520-18-3 kaempferol 
• 358-72-5 dimethylallyl diphosphate 

Downstream Products

• 28610-35-7 3,5-diacetoxy-2-(4-acetoxy-phenyl)-8,8-dimethyl-9,10-dihydro-8H-pyrano[2,3-f]chromen-4-one 

Relevant articles and documents

Dimethylallyl diphosphate: Kaempferol 8-dimethylallyl transferase in Epimedium diphyllum cell suspension cultures

The enzymatic formation of des-O-methylanhydroicaritin from dimethylallyl diphosphate and kaempferol was investigated in the cell-free extract of Epimedium diphyllum cell suspension cultures. The enzyme catalysing the dimethylallyl group transfer to C-8 position of kaempferol (EC 2.5.1.) was membrane-bound and required divalent cations such as Mg2+ and Mn2+. Mg2+ was the most effective for the reaction. The enzyme showed a very broad pH optimum in the alkaline region, pH 7.5-11.0. It required dimethylallyl diphosphate as a sole prenyl donor, but had a rather broad substrate specificity for the prenyl acceptor. Not only kaempferol, but also quercetin (39%), apigenin (60%) and luteolin (34%) were prenylated, whereas kaempferol glycosides, naringenin and genistein were not prenylated. These results suggested that the prenylation reaction of kaempferol precedes the glycosylation step in epimedoside A biosynthesis. The apparent K(m) values for dimethylallyl diphosphate and kaempferol were 0.58 and 0.13 mM, respectively.

The first total synthesis of sophoflavescenol, flavenochromane C, and citrusinol

The first total syntheses of sophoflavescenol (1), flavenochromane C (2), and citrusinol (3) were achieved. These three naturally occurring prenylated or prenyl-cyclized flavonoids have important biological activities such as cytotoxicity against some can

A 2,2-DIMETHYLPYRANOFLAVONOL FROM CITRUS NOBILIS

An investigation of the root bark constituents of Citrus nobilis var. sunki has afforded a sesquiterpene , six coumarins , and four acridone alkaloids together with p-hidroquinone.A new 2,2-dimethylpyranoflavonol was also isolated, identified and named citrusinol. Key Word Index - Citrus nobilis var. sunki; Rutaceae; citrusinol; flavonoids; coumarins; sesquiterpene; acridone alkaloids; homoacridone alkaloids.