28619-41-2 Usage
General Description
(+)-Erythristemine is an alkaloid compound found in certain plant species, including Erythrina subumbrans, Erythrina fusca, and Erythrina berteroana. It has been traditionally used in folk medicine for its potential analgesic and anti-inflammatory properties. Studies have shown that (+)-Erythristemine may have the ability to inhibit the activity of acetylcholinesterase, an enzyme involved in the breakdown of the neurotransmitter acetylcholine, which suggests a potential role in the treatment of neurodegenerative diseases such as Alzheimer's. Additionally, (+)-Erythristemine has been investigated for its potential to modulate the immune system and has shown promising results as a potential immunomodulatory agent. Despite these potential health benefits, further research is needed to fully understand the pharmacological properties and potential therapeutic applications of (+)-Erythristemine.
Check Digit Verification of cas no
The CAS Registry Mumber 28619-41-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,6,1 and 9 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 28619-41:
(7*2)+(6*8)+(5*6)+(4*1)+(3*9)+(2*4)+(1*1)=132
132 % 10 = 2
So 28619-41-2 is a valid CAS Registry Number.
28619-41-2Relevant articles and documents
Stereoselective introduction of oxygen functionalities at the 11β- position of erythrinan skeleton: Total syntheses of (±)-erythristemine and (+)-erythrartine
Isobe,Mohri,Takeda,Suzuki,Hosoi,Tsuda
, p. 197 - 203 (2007/10/02)
Oxidation of 8-oxoerythrinan and 8-oxo-1,7-cycloerythrinan derivatives with 2 mol eq of ceric ammonium nitrate in alcohols or acetic acid gave the corresponding 11β-alkoxy or acetoxy compounds in moderate yield. Thus, (±)- 3,3,15,16-tetramethoxy-1,7-cycloerythrinan-2,8-dione and (+)-erysotramidine gave the corresponding 11β-methoxy and 11β-acetoxy derivatives on oxidation in methanol and in acetic acid, respectively. Those compounds were respectively converted into (±)-erythristemine and (+)-erythrartine in several steps, thus achieving the total synthesis of these alkaloids.
Stereoselective Methoxylation at the 11β-Position of the Erythrinan Skeleton: Total Synthesis of (+/-)-Erythristemine
Isobe, Kimiaki,Mohri, Kunihiko,Takeda, Naoko,Hosoi, Shinzo,Tsuda, Yoshisuke
, p. 1357 - 1358 (2007/10/02)
Treatment of cis-erythrinan-8-one or 1,7-cyclo-cis-erythrinan-8-one with ceric ammonium nitrate in methanol gave the appreciable yields of the corresponding 11β-methoxy compounds; these were converted into the natural 11-oxygenated erythrinan alkaloid, erythristemine, in high yield.
