52358-58-4 Usage
Description
(+)-Erysotramidine is a naturally occurring alkaloid compound isolated from the plant Erysimum cheiranthoides, belonging to the Brassicaceae family. It exhibits a range of biological activities, such as antifungal, antibacterial, anti-inflammatory, and antioxidant properties, along with cytotoxic effects on cancer cells, making it a promising candidate for various medical applications.
Uses
Used in Pharmaceutical Industry:
(+)-Erysotramidine is used as an antifungal and antibacterial agent for its ability to combat fungal and bacterial infections due to its inherent antimicrobial properties.
Used in Anti-inflammatory Applications:
(+)-Erysotramidine is used as an anti-inflammatory agent for its potential to reduce inflammation by inhibiting the production of reactive oxygen species and other inflammatory mediators.
Used in Antioxidant Applications:
(+)-Erysotramidine is used as an antioxidant agent for its capacity to neutralize harmful reactive oxygen species, thereby protecting cells from oxidative damage and related diseases.
Used in Anticancer Applications:
(+)-Erysotramidine is used as a cytotoxic agent for its demonstrated effects on cancer cells, showing potential in the development of novel anticancer therapies.
Used in Cosmetics Industry:
(+)-Erysotramidine could be used as an ingredient in cosmetic products for its anti-inflammatory and antioxidant properties, potentially benefiting skin health and appearance by reducing inflammation and oxidative stress.
Check Digit Verification of cas no
The CAS Registry Mumber 52358-58-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,3,5 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 52358-58:
(7*5)+(6*2)+(5*3)+(4*5)+(3*8)+(2*5)+(1*8)=124
124 % 10 = 4
So 52358-58-4 is a valid CAS Registry Number.
52358-58-4Relevant articles and documents
An asymmetric synthesis of (+)-erysotramidine
Blake, Alexander J.,Gill, Christopher,Greenhalgh, Daniel A.,Simpkins, Nigel S.,Zhang, Fengzhi
, p. 3287 - 3292 (2005)
A new asymmetric total synthesis of the erythrinan alkaloid erysotramidine is described, which uses chiral base desymmetrisation, N-acyliminium addition, and 6-exo-trig radical cyclisation as the key steps. Georg Thieme Verlag Stuttgart.
Synthesis of the erythrina alkaloid erysotramidine
L'Homme, Chloé,Ménard, Marc-André,Canesi, Sylvain
, p. 8481 - 8485 (2015/03/18)
A concise synthesis of erysotramidine (an alkaloid belonging to the erythrina family) was achieved starting with an inexpensive phenol and amine derivative. The synthesis is based on oxidative phenol dearomatizations mediated by a hypervalent iodine reage
Synthesis of the tetracyclic framework of the erythrina alkaloids using a [4 + 2]-cycloaddition/Rh(I)-catalyzed cascade of 2-imidofurans
Padwa, Albert,Wang, Qiu
, p. 7391 - 7402 (2007/10/03)
Several 2-imido substituted furans were found to undergo a rapid intramolecular [4 + 2]-cycloaddition to deliver oxabicyclo adducts in good to excellent yields. By using a Rh(I)-catalyzed ring opening of the resulting oxabicyclic adduct, it was possible t