286463-65-8Relevant articles and documents
Compositions and Methods for Treatment of Cancer
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, (2020/12/17)
Resistance of randomly dispersed and oxygen-starved lung tumor cells to chemo- and radiotherapy constitutes the vast majority recurrences and death from lung cancer. We use sickle cells derived from humans with sickle cell anemia to target oxygen-deprived
Synthesis and antitumor-evaluation of cyclopropyl-containing combretastatin analogs
Fuerst, Rita,Zupko, Istvan,Berenyi, Agnes,Ecker, Gerhard F.,Rinner, Uwe
scheme or table, p. 6948 - 6951 (2010/08/06)
Several derivatives of combretastatin have been prepared bearing a cyclopropyl unit instead of the natural occurring cis-double bond. Final products and synthetic intermediates were evaluated for their cytotoxic properties in two human cancer cell lines.