288251-65-0Relevant articles and documents
Synthesis and insecticidal evaluation of aryl pyrazole 5-fluorouracil compounds
Chen, Yue,Fu, Xiao-Dong,Mu, Hai-Ping,Qin, Xiao-Fei,Wan, Rong
, p. 272 - 279 (2014/06/09)
Twenty eight aryl pyrazole derivatives containing 5-fluorouracil were designed and synthesised via the key intermediate 1-aryl-3-methyl-1H-pyrazole-5- carboxylic acid. The structures of target compounds were confirmed by 1H NMR, FT-IR, EA and t
AMIDE COMPOUNDS AND MEDICINAL USE THEREOF
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, (2010/01/31)
The present invention relates to a compound of the formula wherein R1 is substituted aryl, heteroaryl and the like, R2 and R3 are hydrogen, alkyl, halogen, hydroxyl group and the like, Q is N, CH and the like, W is hydrogen, alkyl, hydroxycarbonylalkyl and the like, X is halogen, cyano, nitro, amino and the like, X' is hydrogen, halogen, cyano, nitro, and Y is alkyl, hydroxyl group, alkoxy, mercapto and the like and a salt thereof, and a medicine containing the said compound. The compound of the present invention shows a superior inhibitory effect on activated lymphocytes proliferation and is useful as an agent for the prophylaxis or treatment of various autoimmune diseases.