289622-32-8

Basic information

• Product Name: 6,7-methylenedioxy-1-(3,4-dimethoxyphenyl)naphthalene-2,3-dicarboxylic acid 2-ethyl ester
• Synonyms: 6,7-methylenedioxy-1-(3,4-dimethoxyphenyl)naphthalene-2,3-dicarboxylic acid 2-ethyl ester
• CAS NO: 289622-32-8
• Molecular Weight: 424.407
• Mol File: 289622-32-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6,7-methylenedioxy-1-(3,4-dimethoxyphenyl)naphthalene-2,3-dicarboxylic acid 2-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-methylenedioxy-1-(3,4-dimethoxyphenyl)naphthalene-2,3-dicarboxylic acid 2-ethyl ester(289622-32-8)
• EPA Substance Registry System: 6,7-methylenedioxy-1-(3,4-dimethoxyphenyl)naphthalene-2,3-dicarboxylic acid 2-ethyl ester(289622-32-8)

Safety Data

• Hazardous Substances Data: 289622-32-8(Hazardous Substances Data)

Upstream product

• 289622-27-1 diethyl 6,7-methylenedioxy-1-(3,4-dimethoxyphenyl)naphthalene-2,3-dicarboxylate 
• 7071-15-0 diethyl 2-(diethoxyphosphoryl)succinate 
• 473253-65-5 3,4-dimethoxybenzyl-(6-formylbenzo[1,3]dioxol-5-yl)methanone 

Downstream Products

• 31888-76-3 1-(3,4-dimethoxyphenyl)-3-hydroxymethyl-6,7-methylenedioxynaphthalene-2-carboxylic acid lactone 
• 5707-96-0 retrochinensin 

Relevant articles and documents

A new benzannulation reaction and its application in the multiple parallel synthesis of arylnaphthalene lignans

A new aromatic annulation reaction based on sequential Horner-Emmons and Claisen condensation reactions is described. The method is high yielding and provides a rapid entry to arylnaphthalenes. The lignan natural products justicidin B 1, retrojusticidin B 2, taiwanin C 3, justicidin E 4, chinensin 5 and retrochinensin 6 have all been synthesised in good overall yield using this protocol, demonstrating its potential in multiple parallel synthesis. The selective oxidation of diols 34-36 to the corresponding retrolactones with barium manganate(VI) is also noteworthy.