473253-65-5

Basic information

• Product Name: 3,4-dimethoxybenzyl-(6-formylbenzo[1,3]dioxol-5-yl)methanone
• Synonyms: 3,4-dimethoxybenzyl-(6-formylbenzo[1,3]dioxol-5-yl)methanone
• CAS NO: 473253-65-5
• Molecular Weight: 314.295
• Mol File: 473253-65-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,4-dimethoxybenzyl-(6-formylbenzo[1,3]dioxol-5-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dimethoxybenzyl-(6-formylbenzo[1,3]dioxol-5-yl)methanone(473253-65-5)
• EPA Substance Registry System: 3,4-dimethoxybenzyl-(6-formylbenzo[1,3]dioxol-5-yl)methanone(473253-65-5)

Safety Data

• Hazardous Substances Data: 473253-65-5(Hazardous Substances Data)

Upstream product

• 6642-34-8 6-bromopiperonyl alcohol 
• 473253-67-7 (3,4-dimethoxyphenyl)-(6-hydroxymethyl-benzo[1,3]dioxol-5-yl)methanol 

Downstream Products

• 66130-46-9 dimethyl 6,7-methylenedioxy-(3',4'-dimethoxyphenyl)naphthalene-2,3-dicarboxylate 
• 289622-32-8 6,7-methylenedioxy-1-(3,4-dimethoxyphenyl)naphthalene-2,3-dicarboxylic acid 2-ethyl ester 
• 289622-27-1 diethyl 6,7-methylenedioxy-1-(3,4-dimethoxyphenyl)naphthalene-2,3-dicarboxylate 
• 5707-96-0 retrochinensin 
• 31888-76-3 1-(3,4-dimethoxyphenyl)-3-hydroxymethyl-6,7-methylenedioxynaphthalene-2-carboxylic acid lactone 
• 42923-60-4 2,3-bis-(hydroxymethyl)-6,7-methylenedioxy-1-(3',4'-dimethoxyphenyl)-naphthalene 

Relevant articles and documents

A new benzannulation reaction and its application in the multiple parallel synthesis of arylnaphthalene lignans

A new aromatic annulation reaction based on sequential Horner-Emmons and Claisen condensation reactions is described. The method is high yielding and provides a rapid entry to arylnaphthalenes. The lignan natural products justicidin B 1, retrojusticidin B 2, taiwanin C 3, justicidin E 4, chinensin 5 and retrochinensin 6 have all been synthesised in good overall yield using this protocol, demonstrating its potential in multiple parallel synthesis. The selective oxidation of diols 34-36 to the corresponding retrolactones with barium manganate(VI) is also noteworthy.