289677-42-5Relevant articles and documents
Conformationally restricted analogues designed for selective inhibition of GAR Tfase versus thymidylate synthase or dihydrofolate reductase
Boger, Dale L.,Labroli, Marc A.,Marsilje, Thomas H.,Jin, Qing,Hedrick, Michael P.,Baker, Stephen J.,Shim, Jae Hoon,Benkovic, Stephen J.
, p. 1075 - 1086 (2000)
The synthesis and evaluation of a series of conformationally restricted analogues of 10-formyl-tetrahydrofolate as potential inhibitors of glycinamide ribonucleotide transformylase (GAR Tfase) or aminoimidazole carboxamide transformylase (AICAR Tfase) are reported. (C) 2000 Elsevier Science Ltd.