13518-55-3 Usage
Description
5-(2-Chloroethyl)-1H-imidazole is an organic compound with the molecular formula C7H8ClN2. It is characterized by the presence of an imidazole ring, which is a five-membered ring containing two nitrogen atoms, and a chloroethyl group attached to the 5th position of the imidazole. 5-(2-Chloroethyl)-1H-imidazole is known for its potential applications in various chemical and pharmaceutical processes due to its unique structure and reactivity.
Uses
Used in Chemical Synthesis:
5-(2-Chloroethyl)-1H-imidazole is used as a reagent or reactant in the preparation of poly(vinylimidazolium)s-diazabicycloundecene-zinc(II) bromide catalyst systems. These catalyst systems are essential for the cycloaddition of carbon dioxide to epoxides, a crucial reaction in the synthesis of various organic compounds and materials.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5-(2-Chloroethyl)-1H-imidazole can be utilized as a building block or intermediate for the synthesis of various drug molecules. Its unique structure and reactivity make it a valuable component in the development of new therapeutic agents, particularly those targeting specific biological pathways or receptors.
Used in Research and Development:
5-(2-Chloroethyl)-1H-imidazole is also used in research and development for the exploration of new chemical reactions and the synthesis of novel compounds. Its versatility and potential for modification make it an attractive candidate for studying new reaction mechanisms and developing innovative synthetic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 13518-55-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,5,1 and 8 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 13518-55:
(7*1)+(6*3)+(5*5)+(4*1)+(3*8)+(2*5)+(1*5)=93
93 % 10 = 3
So 13518-55-3 is a valid CAS Registry Number.
13518-55-3Relevant articles and documents
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Turner
, p. 3476 (1949)
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Schunack
, p. 517,522 (1974)
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Poly(4-vinylimidazolium)s/diazabicyclo[5.4.0]undec-7-ene/zinc(II) bromide-catalyzed cycloaddition of carbon dioxide to epoxides
Seo, Ue Ryung,Chung, Young Keun
supporting information, p. 1955 - 1961 (2014/07/07)
Poly(4-vinylimidazolium)s, derived from the self-immobilization of 4-vinylimidazoliums, with diazabicyclo[5.4.0]undec-7-ene (DBU) and zinc bromide (ZnBr2) are used as a highly efficient catalyst for the chemical fixation of carbon dioxide. This catalytic system has been applied for the preparation of cyclic carbonates from terminal epoxides and carbon dioxide. Many functional groups, including chloro, vinyl, ether, and hydroxy groups are well tolerated in the reactions. Moreover, the catalytic system was found to catalyze the conversion of more sterically congested epoxides which are generally considered to be challenging substrates for fabricating the cyclic organic carbonates. In addition, the disubstituted epoxides are found to react with retention of configuration. The polymer precatalyst is easily recovered and reused. A plausible reaction mechanism is proposed.
