2902-65-0Relevant articles and documents
Regioselective Oxidative Arylation of Fluorophenols
Yu, Congjun,Patureau, Frederic W.
, p. 18530 - 18534 (2019)
A metal free and highly regioselective oxidative arylation reaction of fluorophenols is described. The relative position of the fluoride leaving group (i.e., ortho or para) controls the 1,2 or 1,4 nature of the arylated quinone product, lending versatilit
A peptide bromoiodinane approach for asymmetric bromolactonization
Whitehead, Daniel C.,Fhaner, Matthew,Borhan, Babak
supporting information; experimental part, p. 2288 - 2291 (2011/05/16)
A series of 37 peptides containing an iodo-aryl amide active site were generated by means of both solid phase and conventional synthesis. These peptides were screened for asymmetric induction in the bromolactonization of 4-phenyl-4-pentenoic acid based on the generation of chiral bromoiodinane bromenium sources. The study culminated in the discovery of a tri-peptide iodo-aryl amide that effected the desired bromolactonization in quantitative conversion with 24% ee. The experiments disclosed herein provided valuable insight that ultimately facilitated the development of more synthetically useful enantioselective halocyclization methodology.
The Synthesis of Substituted 9-Oxoacridan-4-carboxylic Acids; Part 2. The Use of 2-Iodoisophthalic Acid in the Jourdan-Ullmann Reaction
Rewcastle, Gordon W.,Denny, William A.
, p. 217 - 220 (2007/10/02)
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