29064-82-2

Basic information

• Product Name: 3-BROMO-4-CHLOROTHIENO[3,2-C]PYRIDINE
• Synonyms: 3-BROMO-4-CHLOROTHIENO[3,2-C]PYRIDINE;3-BroMo-4-chlorothieno[3,...
• CAS NO: 29064-82-2
• Molecular Formula: C₇H₃BrClNS
• Molecular Weight: 248.53
• Product Categories: Heterocycle-Pyridine series
• Mol File: 29064-82-2.mol
• Article Data: 10

Chemical Properties

• Melting Point: 161-163℃
• Boiling Point: 355.2±37.0 °C(Predicted)
• Appearance: /
• Density: 1.849
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -1.47±0.40(Predicted)
• CAS DataBase Reference: 3-BROMO-4-CHLOROTHIENO[3,2-C]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-4-CHLOROTHIENO[3,2-C]PYRIDINE(29064-82-2)
• EPA Substance Registry System: 3-BROMO-4-CHLOROTHIENO[3,2-C]PYRIDINE(29064-82-2)

Safety Data

• Hazard Codes: T
• Statements: 25-36
• Safety Statements: 26-45
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 29064-82-2(Hazardous Substances Data)

Usage

General Description

3-Bromo-4-chlorothieno[3,2-c]pyridine is a chemical compound with the molecular formula C7H3BrClNS. It is a heterocyclic compound with a thieno[3,2-c]pyridine backbone, and it contains a bromine and a chlorine atom as substituents. This chemical is often used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Its unique structure and reactivity make it a valuable tool for creating new molecules with potential biological activity. Additionally, 3-Bromo-4-chlorothieno[3,2-c]pyridine is often utilized in research laboratories as a reagent for chemical reactions and as a starting material for the preparation of more complex compounds.

Upstream product

• 799293-83-7 3-bromo-4-hydroxy-[3,2-c]-thienopyridine 
• 1150566-09-8 4-bromo-thiophene-3-carboxylic acid (2,2-dimethoxy-ethyl)-amide 
• 16694-17-0 4-bromo-3-thiophenecarboxylic acid 
• 799293-83-7 3-bromothieno[3,2-c]pyridin-4(5H)-one 
• 103686-16-4 trans-3-(4-bromothiophen-2-yl)propenoic acid 
• 18791-75-8 4-Bromothiophen-2-aldehyde 
• 799293-81-5 trans-3-(4-bromothiophen-2-yl)-acryloyl azide 

Downstream Products

• 799293-85-9 3-bromo-4-amino-[3,2-c]-thienopyridine 

Relevant articles and documents

NEW BICYCLIC DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Compounds of formula (I); wherein R1, R2, R3, R4, R5, R6, R7, R8, R14, W, A and n are as defined in the description. Medicaments.

Thienopyridine urea inhibitors of KDR kinase

A series of substituted thienopyridine ureas was prepared and evaluated for enzymatic and cellular inhibition of KDR kinase activity. Several of these analogs, such as 2, are potent inhibitors of KDR (10 nM) in both enzymatic and cellular assays. Further

Discovery of thienopyridines as Src-family selective Lck inhibitors

We describe the identification, SAR, and in vivo pharmacology of a new series of Src-family selective Lck inhibitors. These thienopyridines were designed based on a desire to access the unique residues in the extended hinge region of Lck.