799293-83-7

Basic information

• Product Name: 3-broMo-4H,5H-thieno[3,2-c]pyridin-4-one
• Synonyms: 3-broMo-4H,5H-thieno[3,2-c]pyridin-4-one;3-BroMothieno[3,2-c]pyridin-4(5H)-one;3-broMo-4-hydroxy-[3,2-c]-thienopyridine;3-BROMO-4-HYDROXYTHIENO[3,2-C]PYRIDINE;3-Bromothieno[3,2-c]pyridin-4-ol;3-Bromothieno[3,2-c]pyridin-4(5H)
• CAS NO: 799293-83-7
• Molecular Formula: C₇H₄BrNOS
• Molecular Weight: 230.08176
• Mol File: 799293-83-7.mol
• Article Data: 12

Chemical Properties

• Melting Point: 273-278°C
• Boiling Point: 468.6±45.0 °C(Predicted)
• Appearance: /
• Density: 1.801±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 12.09±0.20(Predicted)
• CAS DataBase Reference: 3-broMo-4H,5H-thieno[3,2-c]pyridin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-broMo-4H,5H-thieno[3,2-c]pyridin-4-one(799293-83-7)
• EPA Substance Registry System: 3-broMo-4H,5H-thieno[3,2-c]pyridin-4-one(799293-83-7)

Safety Data

• Hazard Codes: T,C
• Statements: 25-34-36
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3260 8 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 799293-83-7(Hazardous Substances Data)

Usage

General Description

3-Bromo-4H,5H-thieno[3,2-c]pyridin-4-one is a chemical compound with the molecular formula C8H5BrNOS. It is a heterocyclic organic compound that contains a thienopyridine ring system and a bromine substitution at the 3-position. 3-broMo-4H,5H-thieno[3,2-c]pyridin-4-one has potential applications in the field of pharmaceuticals and materials science. It may be used as a building block in the synthesis of novel organic compounds with useful properties, and it could also be investigated for its potential biological activity. Further research and experimentation may reveal the full range of potential uses for this chemical.

Upstream product

• 1150566-09-8 4-bromo-thiophene-3-carboxylic acid (2,2-dimethoxy-ethyl)-amide 
• 799293-81-5 trans-3-(4-bromothiophen-2-yl)-acryloyl azide 
• 16694-17-0 4-bromo-3-thiophenecarboxylic acid 
• 103686-16-4 trans-3-(4-bromothiophen-2-yl)propenoic acid 
• 18791-75-8 4-Bromothiophen-2-aldehyde 

Downstream Products

• 799293-85-9 3-bromo-4-amino-[3,2-c]-thienopyridine 
• 29064-82-2 3-bromo-4-chloro-[3,2-c]-thienopyridine 

Relevant articles and documents

Thermal synthesis of 3-bromothieno[3,2-c]pyridin-4-(5h)-one: A telescoped procedure with tributylamine

3-Bromothieno[3,2-c]pyridine-4-(5H)-one (1) was prepared from (2E)-3-(4-bromo-2-thienyl)-2- propenoic acid (3) by the Eloy-Deryckere thermal benzo/heteropyridinone synthesis. A telescoped procedure was developed, which reduces some of the risk associated with the classic procedure. Use of tributylamine as an additive in this process was shown to facilitate E/Z-isomerization of the intermediate vinyl isocyanate and lower the temperature necessary for the overall thermal process.

NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A

The present invention relates to novel compounds of the formula I which are inhibitors of phosphodiesterase type 10A and to their use for the manufacture of a medicament and which thus are suitable for treating or controlling of medical disorders selected from neurological disorders and psychiatric disorders, for ameliorating the symptoms associated with such disorders and for reducing the risk of such disorders

Thienopyridine urea inhibitors of KDR kinase

A series of substituted thienopyridine ureas was prepared and evaluated for enzymatic and cellular inhibition of KDR kinase activity. Several of these analogs, such as 2, are potent inhibitors of KDR (10 nM) in both enzymatic and cellular assays. Further