29113-63-1

Basic information

• Product Name: ETHYL 2,5-DIMETHYL-3-FUROATE
• Synonyms: ETHYL 2,5-DIMETHYL-3-FUROATE;ETHYL 2,5-DIMETHYL-FURAN-3-CARBOXYLATE
• CAS NO: 29113-63-1
• Molecular Formula: C₉H₁₂O₃
• Molecular Weight: 168.19
• Mol File: 29113-63-1.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 257.12°C (rough estimate)
• Flash Point: 83°C
• Appearance: /
• Density: 1.0478
• Vapor Pressure: 0.213mmHg at 25°C
• Refractive Index: 1.4686 (estimate)
• CAS DataBase Reference: ETHYL 2,5-DIMETHYL-3-FUROATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2,5-DIMETHYL-3-FUROATE(29113-63-1)
• EPA Substance Registry System: ETHYL 2,5-DIMETHYL-3-FUROATE(29113-63-1)

Safety Data

• Hazardous Substances Data: 29113-63-1(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 29, p. 4987, 1988 DOI: 10.1016/S0040-4039(00)80660-7

InChI:InChI=1/C9H12O3/c1-4-11-9(10)8-5-6(2)12-7(8)3/h5H,4H2,1-3H3

Upstream product

• 1117-96-0 Diazoethan 
• 636-44-2 2,5-dimethylfuran-3-carboxylic acid 
• 122132-51-8 3-ethoxycarbonyl-5-iodomethyl-2-methyl-4,5-dihydrofuran 
• 141-97-9 ethyl acetoacetate 
• 78-95-5 chloroacetone 
• 2049-86-7 Diethyl 2,3-diacetylsuccinate 
• 96121-86-7 ethyl 2-propionylpent-4-enoate 
• 32596-02-4 ethyl 2,5-dimethyl-4,5-dihydrofuran-3-carboxylate 
• 90674-91-2 ethyl 2-acetyl-4-bromopent-4-enoate 
• 1007476-32-5 sodium ethyl acetylacetate enolate 
• 36600-70-1 ethyl 2-acetylpent-4-ynoate 
• 10544-63-5 ethyl crotonate 
• 67556-28-9 ethyl 2-acetyl-4-bromo-2-pentenoate 
• 67556-10-9 ethyl 2-acetyl-2-pentenoate 

Downstream Products

• 159881-93-3 2,5-dimethyl-furan-3-carboxylic acid hydrazide 
• 887576-69-4 4-iodo-2,5-dimethyl-furan-3-carboxylic acid ethyl ester 
• 1003-96-9 2,5-dimethyl-3-(hydroxymethyl)furan 
• 865376-68-7 2,5-dimethyl-4-(2-methoxyphenyl)furan-3-carboxylic acid ethyl ester 
• 108123-02-0 2,5-dimethyl-4-phenylfuran-3-carboxylic acid ethyl ester 
• 50990-93-7 2,5-dimethyl-furan-3-carbonyl chloride 

Relevant articles and documents

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Preparation of polysubstituted dihydrofurans through a PhI(OAc)2-promoted haloenolcyclization of olefinic dicarbonyl compounds

A metal-free cyclization of olefinic dicarbonyl compounds for the synthesis of various 5-halomethyl-4,5-dihydrofurans is presented. Using (diacetoxyiodo)benzene as the reaction promoter and halotrimethylsilane as the halogen source, the intramolecular hal

Understanding the Scope of Feist–Bénary Furan Synthesis: Chemoselectivity and Diastereoselectivity of the Reaction Between α-Halo Ketones and β-Dicarbonyl Compounds

Feist–Bénary furan synthesis, the reaction between α-halocarbonyl and β-dicarbonyl compounds, has been known as an efficient method for generating many different types of furans containing a carbonyl group at C-3. However, it has also been reported that, under similar reaction conditions, intermediate tricarbonyl species could be further converted to alternative furan isomers through the application of a Paal–Knorr synthesis. In this manuscript, we investigate the chemoselectivity and diastereoselectivity of furan synthesis from α-halo ketones and β-dicarbonyl compounds, by carrying out the separation and characterization of the intermediates involved in the reaction. Additionally, a one-pot Feist–Bénary furan synthesis from α-halo ketones and β-dicarbonyl compounds without any base or solvent has also been developed.